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An in vitro study of mesenchyme–islet cell interactions in islet neogenesis: A model for tissue replacement therapy in diabetes mellitus
(Stellenbosch : Stellenbosch University, 2017-12)
ENGLISH ABSTRACT : Shortages of donor islets, immune rejection, and the need for life-long immuno-suppressors remain the clinical challenges of islet transplantation in the treatment of diabetes mellitus. An alternative ...
Hyperglycaemia and its implication on the Pancreatic islet microvasculature in diabetic rat models
(Stellenbosch : Stellenbosch University, 2020-12)
SUMMARY BACKGROUND: Despite the considerable progress made in the treatment of diabetes mellitus, vascular damage remains the leading cause of patient death. The mechanisms underlying vascular abnormalities in ...