Browsing Doctoral Degrees (General Internal Medicine) by Title
Now showing items 6-15 of 15
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Familial adult myoclonus epilepsy : a clinical, neurophysiological and genetic study of a familial form of myoclonic epilepsy
(Stellenbosch : University of Stellenbosch, 2009-12)ENGLISH ABSTRACT: Progressive Myoclonic Epilepsies (PME) are characterized by progressive neurological impairment with myoclonus, seizures and dementia. In contradistinction, Familial Adult Myoclonic Epilepsy (FAME) is ... -
Hepatitis-B-associated glomerular disease : a clinicopathological study of Hepatitis B virus associated Membranous Glomerulonephritis in Namibian and South African children 1974 - 2005 and a comparison with Hepatitis B associated Membranous Glomerulonephritis as well as Idiopathic Membranous Glomerulonephritis in adults
(Stellenbosch : Stellenbosch University, 2011-12)ENGLISH ABSTRACT: Background and Objective: The most common cause of severe proteinuria/nephrotic syndrome (NS) in children worldwide is minimal change disease (MCD). This is also the pattern observed in white and Indian ... -
A historical perspective of allogeneic and autologous immunohaematopoietic stem cell transplantation in South Africa and a study of the non-haematologic consequences
(Stellenbosch : Stellenbosch University, 2015-03)ENGLISH ABSTRACT: HISTORICAL PERSPECTIVE Stem cell therapy was commenced after using rabbits as research models. Once this process was successful, the first human transplant was done in 1974. Certain prerequisites were ... -
The immunopathogenesis and treatment of tuberculous pericardial effusions in a population with a high prevalence of infection with the human immunodeficiency virus
(Stellenbosch : University of Stellenbosch, 2005-12)Mycobacterium tuberculosis (M. tuberculosis) accounts for more adult deaths than any other infectious agents. The present study included 162 patients with tuberculous pericarditis; 50% of the tuberculous pericarditis ... -
An investigation of the clinical profile and extent of Long QT Syndrome (LQTS) associated with the KCNQ1-A341V mutation in South Africa and with the KCNH2-A1116V mutation in an Italian family and the role that autonomic nervous system (ANS) activity and genetics play in clinical variability
(Stellenbosch : University of Stellenbosch, 2007-12)Background Although great progress has been made in defining genes conferring the majority of genetic risk in Long QT Syndrome (LQTS) patients, there remains a substantial challenge to explain the widely observed ... -
A longitudinal study of the stability of the dentition following orthodontic treatment
(Stellenbosch : Stellenbosch University, 1992)ENGLISH ABSTRACT: The maintenance of dental alignment following orthodontic treatment has been, and continues to be, a challenge for the orthodontist (McReynolds and Little, 1991). Orthodontists should endeavour to ... -
Refinements and innovations in biopsy and analysis techniques for pleural and lung disease
(Stellenbosch : University of Stellenbosch, 2007-12)1.1. Background Tumors arising from the lung, pleura, or chest wall are a frequent problem in clinical pulmonary medicine. Most lesions are either infectious, neoplastic or granulomatous in nature, but a variety of other ... -
The role of phosphatase activity and expression in glucocorticoid modulation of preosteoblasts
(Stellenbosch : University of Stellenbosch, 2011-12)ENGLISH ABSTRACT: The increase in the prescription and use of glucocorticoids (GCs) to treat various diseases and resulting decrease in bone density and development of osteoporosis is of growing concern. Glucocorticoid-induced ... -
A study of non-alcoholic fatty liver disease (NAFLD) in South African patients and analysis of candidate genes in insulin resistance and fatty acid oxidation.
(Stellenbosch : Stellenbosch University, 2008-12)Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease in Western countries, extending from steatosis (FLD) to steatohepatitis (NASH). Differentiation between NASH and nonprogressive NAFLD ... -
Ultrasound-assisted transthoracic diagnostic techniques
(Stellenbosch : University of Stellenbosch, 2011-12)ENGLISH ABSTRACT: Although transthoracic ultrasonography is a well established modality, it is still underutilised by chest physicians. The aim of this research project was to investigate the feasibility, diagnostic yield ...
