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Phylogenetic analysis of HIV-1 in Mpumalanga
(Stellenbosch : Stellenbosch University, 2013-03)The diversity of HIV-1 sequences derived from patients in Bushbuckridge, Mpumalanga, was investigated. The gag p24, pol p10 and p66/p51, pol p31 and env gp41 gene fragments from 51 patients were amplified and sequenced. ... -
The apoptotic potential of different HIV-1 subtype C Tat mutations in cell culture
(Stellenbosch : Stellenbosch University, 2013-03)The efficiency in which HIV-1 can infect, spread and evade the attack of therapeutic agents can be attributed to a high mutation rate and frequent recombination events. These factors have collectively contributed to the ...