Now showing items 1-9 of 9
Highlights from the 3rd international HIV/viral hepatitis Co-infection meeting - HIV/viral hepatitis : improving diagnosis, antiviral therapy and access
(BioMed Central, 2017-04-20)
The International AIDS Society convened the 3rd International HIV/Viral Hepatitis Co-Infection Meeting on 17 July 2016 as part of the pre-conference program preceding the 21st International AIDS Conference held in Durban, ...
Identifying recent HIV infections : from serological assays to genomics
In this paper, we review serological and molecular based methods to identify HIV infection recency. The accurate identification of recent HIV infection continues to be an important research area and has implications for ...
The HIV/HBV co-infected patient : time for proactive management
(Health and Medical Publishing Group, 2015-02)
Hepatitis B virus (HBV) infection affects around 240 million people worldwide, with the highest prevalence of disease in Africa and Asia. Hepatocellular carcinoma (HCC) is the second most common cancer in men in Africa, ...
HIV-1 viral load assays for resource-limited settings : clades matter
(Public Library of Science Medicine, 2006-12)
Molecular characterization of HIV-1 subtype C gp-120 regions potentially involved in virus adaptive mechanisms
The role of variable regions of HIV-1 gp120 in immune escape of HIV has been investigated. However, there is scant information on how conserved gp120 regions contribute to virus escaping. Here we have studied how molecular ...
Deciphering multiplicity of HIV-1C infection : transmission of closely related multiple viral lineages
(Public Library of Science, 2016-11-28)
Background: A single viral variant is transmitted in the majority of HIV infections. However, about 20% of heterosexually transmitted HIV infections are caused by multiple viral variants. Detection of transmitted HIV ...
HBV and HIV viral load but not microbial translocation or immune activation are associated with liver fibrosis among patients in South Africa
(BioMed Central, 2018-05-08)
Background: Co-infection with HIV negatively impacts the progression of chronic hepatitis B virus (HBV) infection, including causing rapid progression to liver fibrosis. Sub-Saharan Africa represents arguably the most ...
Hepatitis B virus-associated hepatocellular carcinoma in South Africa in the era of HIV
(BMC (part of Springer Nature), 2020-07-13)
Background: Patients co-infected with hepatitis B virus (HBV) and the human immunodeficiency virus (HIV) are at risk of developing hepatocellular carcinoma (HCC). In sub-Saharan Africa, the overlap between high HIV and ...
HIV-1C env and gag variation in the cerebrospinal fluid and plasma of patients with HIV-associated cryptococcal meningitis in Botswana
ENGLISH ABSTRACT: HIV-1 compartmentalization in reservoir sites remains a barrier to complete HIV eradication. It is unclear whether there is variation in HIV-1 env and gag between cerebrospinal fluid (CSF) and plasma ...