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Cytokine production in patients with tuberculous pericarditis

Burgess L.J.; Reuter H.; Carstens M.E.; Taljaard J.J.F.; Doubell A.F. (2002)

SETTING: An academic hospital in the Western Cape, South Africa. OBJECTIVE: To evaluate cytokine production (interferon-gamma [IFN-γ], interleukin-1 [IL-1], interleukin-2 [IL-2], interleukin-6 [IL-6], interleukin-10 [IL-10], ...

Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures a prospective, controlled, randomized study of four hundred and fifty patients

Govender S.; Csimma C.; Genant H.K.; Valentin-Opran A.; Amit Y.; Arbel R.; Aro H.; Atar D.; Bishay M.; Borner M.G.; Chiron P.; Choong P.; Cinats J.; Courtenay B.; Feibel R.; Geulette B.; Govender S.; Gravel C.; Haas N.; Raschke M.; Hammacher E.; Van der Velde D.; Hardy P.; Holt M.; Josten C.; Ketterl R.L.; Lindeque B.; Lob G.; Mathevon H.; McCoy G.; Marsh D.; Miller R.; Munting E.; Oevre S.; Nordsletten L.; Patel A.; Pohl A.; Rennie W.; Reynders P.; Rommens P.M.; Rondia J.; Rossouw W.C.; Daneel P.J.; Ruff S.; Ruter A.; Santavirtal S.; Schidhauer T.A.; Gekle C.; Schnettler R.; Segal D.; Seiler H.; Snowdowne R.B.; Stapert J.; Taglang G.; Verdonik R.; Vogels L.; Weckbach A.; Wentzensen A.; Wisriewsk T. (2002)

Background: The treatment of open fractures of the tibial shaft is often complicated by delayed union and non-union. The objective of this study was to evaluate the safety and efficacy of the use of recombinant human bone ...

Phase II trial of ZD0473 as second-line therapy in mesothelioma

Giaccone G.; O'Brien M.E.R.; Byrne M.J.; Bard M.; Kaukel E.; Smit B. (2002)

A phase II, open-label, non-comparative, multicentre trial of the platinum analogue ZD0473 as second-line therapy for pleural mesothelioma has been completed. The objectives were to evaluate the activity and tolerability ...

Effects of folic acid and zinc sulfate on male factor subfertility: A double-blind, randomized, placebo-controlled trial

Wong W.Y.; Merkus H.M.W.M; Thomas C.M.G; Menkveld R.; Zielhuis G.A.; Steegers-Theunissen R.P.M (2002)

Objective: To study the effects of folic acid and zinc sulfate treatment on semen variables in fertile and subfertile men. Design: Double-blind, placebo-controlled interventional study. Setting: Two outpatient fertility ...

Prospective evaluation of the American Urological Association symptom index and peak urinary flow rate for the followup of men with known urethral stricture disease

Heyns C.F.; Marais D.C. (2002)

Purpose: We prospectively evaluated the American Urological Association (AUA) symptom index and maximum urine flow for predicting urethral stricture recurrence in men with a previous diagnosis of urethral stricture disease. ...

Moclobemide is effective and well tolerated in the long-term pharmacotherapy of social anxiety disorder with or without comorbid anxiety disorder

Stein D.J.; Cameron A.; Amrein R.; Montgomery S.A. (2002)

Social phobia (social anxiety disorder) is a highly prevalent and chronic disorder that is associated with significant comorbidity and disability. Despite recent advances in the pharmacotherapy of the disorder, there is a ...

Depressive symptoms at baseline predict fewer negative symptoms at follow-up in patients with first-episode schizophrenia

Oosthuizen P.; Emsley R.A.; Roberts M.C.; Turner J.; Keyter L.; Keyter N.; Torreman M. (2002)

There is uncertainty regarding the prognostic value of depressive symptoms in schizophrenia, having previously been associated with both favourable and poor outcome. This study investigated the relationship between baseline ...