Now showing items 1-10 of 10
Interferon-gamma release assays for the detection of Mycobacterium tuberculosis infection in children with cancer
SETTING: The paediatric oncology unit at Tygerberg Children's Hospital, South Africa. OBJECTIVES: To assess the use of the tuberculin skin test (TST) and two commercial interferon-gamma release assays (IGRAs) for the ...
Fine-needle aspiration biopsy: A fi rst-line diagnostic procedure in paediatric tuberculosis suspects with peripheral lymphadenopathy?
OBJECTIVE: To evaluate the diagnostic yield and time to diagnosis of fi ne-needle aspiration biopsy (FNAB) vs. routine respiratory specimens collected from children with a palpable peripheral lymph node mass and symptoms ...
Childhood drug-resistant tuberculosis in the Western Cape Province of South Africa
Aim: Continued surveillance of drug resistance amongst children presenting with culture-confirmed tuberculosis to a tertiary care hospital and to community clinics. Methods: Drug susceptibility testing for isoniazid and ...
Diagnosing mycobacterial lymphadenitis in children using fine needle aspiration biopsy: Cytomorphology, ZN staining and autofluorescence-making more of less
Although the incidence of TB has stabilized or declined in most world regions, it is increasing in Africa, Southeast Asia, and the Eastern Mediterranean, fuelled by the HIV pandemic. More than 4,000 people died daily from ...
Tuberculosis in women and children
[No abstract available]
Beijing and Haarlem genotypes are overrepresented among children with drug-resistant tuberculosis in the Western Cape province of South Africa
Drug resistance among children with culture-confirmed tuberculosis (TB) provides an accurate measure of transmitted drug resistance within the community. We describe the genotype diversity in children with culture-confirmed ...
Improvement in mycobacterial yield and reduced time to detection in pediatric samples by use of a nutrient broth growth supplement
There is an urgent need to improve the methods used for the bacteriological diagnosis of childhood mycobacterial disease. This study compared the mycobacterial yields and the times to detection (in days) of mycobacteria ...
Adult-type pulmonary tuberculosis in children 10-14 years of age
We report 8 children (10-14 years of age) who were diagnosed with tuberculosis at their local primary health care clinic from July to September 2004, after routine sputum testing was extended to all children older than 10 ...
Absence of an association between Mycobacterium tuberculosis genotype and clinical features in children with tuberculous meningitis
OBJECTIVES: Animal studies point to increased virulence of certain mycobacterial strains, notably those of the Beijing genotype. There are limited data on mycobacterial genotypic diversity in children with tuberculous ...
Age and the epidemiology and pathogenesis of tuberculosis
[No abstract available]