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Isoenzymes of adenosine deaminase in pleural effusions: A diagnostic tool?

Carstens M.E.; Burgess L.J.; Maritz F.J.; Taljaard J.J.F. (1998)

SETTING: Tygerberg Hospital, an academic teaching hospital, Republic of South Africa. OBJECTIVE: To identify the adenosine deaminase (ADA) isoenzymes as a diagnostic tool for tuberculosis in pleural effusions with increased ...

Correlation between p53 gene mutation, p53 protein labeling and PCNA expression in oral squamous cell carcinomas

Van Heerden W.F.P.; Van Rensburg E.J.; Hemmer J.; Raubenheimer E.J.; Engelbrecht S. (1998)

Background: The prevalence of oral squamous cell carcinoma (OSCC) among the Black community in South Africa is unacceptably high. The association between p53 protein, and PCNA overexpression and the presence of p53 gene ...

Significance of antisperm antibodies in female serum in a gamete intrafallopian transfer program

Vandendael A.; Kruger T.F.; De Villiers A.; Menkveld R.; Lombard C.J. (1998)

The influence of antisperm antibodies in the female serum on fertilization and pregnancy rate in patients undergoing GIFT was assessed. A study group of 52 couples (69 cycles) with significant levels of antisperm antibodies ...

Allelic imbalance and microsatellite instability of the DCC gene in colorectal cancer in patients under the age of 35 using fluorescent DNA technology

Chetty R.; Naidoo R.; Schneider J. (1998)

Aim-To assess allelic imbalance and microsatellite instability in the region of the 'deleted in colorectal cancer' (DCC) gene on chromosome 18q using fluorescent DNA technology in colorectal cancer in patients under the ...

Randomised controlled trial of Helicobacter pylori eradication in patients on non-steroidal anti-inflammatory drugs: HELP NSAIDs study

Hawkey C.J.; Tulassay Z.; Szczepanski L.; Van Rensburg C.J.; Filipowicz-Sosnowska A.; Lanas A.; Wason C.M.; Peacock R.A.; Gillon K.R.W. (1998)

Background. The effect of Helicobacter pylori in patients receiving non-steroidal anti-inflammatory drugs (NSAIDs) is unclear. We investigated the effects of H pylori eradication in patients with current or previous peptic ...

A comparison of omeprazole with ranitidine for ulcers associated with nonsteroidal antiinflammatory drugs

Yeomans N.D.; Tulassay Z.; Juhasz L.; Racz I.; Howard J.M.; Van Rensburg C.J.; Swannell A.J.; Hawkey C.J. (1998)

Background: Suppressing acid secretion is thought to reduce the risk of ulcers associated with regular use of nonsteroidal antiinflammatory drugs (NSAIDs), but the best means of accomplishing this is uncertain. Methods: ...

Detection and subtyping of human herpesvirus-8 in renal transplant patients before and after remission of Kaposi's sarcoma

Moosa M.R.; Treurnicht F.K.; Van Rensbubg E.J.; Schneider J.W.; Jordaan H.F.; Engelbrecht S. (1998)

Background. Kaposi's sarcoma (KS) is a complication of renal transplantation. If the human herpesvirus-8 (HHV-8) causes KS, the virus should be present in all KS lesions and be drastically reduced or cleared from involved ...

p53 and p16/CDKN2 gene mutations in esophageal tumors from a high- incidence area in South Africa

Gamieldien W.; Victor T.C.; Mugwanya D.; Stepien A.; Gelderblom W.C.A.; Marasas W.F.O.; Geiger D.H.; Van Helden P.D. (1998)

Squamous cell carcinoma of the esophagus has an uneven geographic distribution, with a high incidence in the Transkei region of Eastern Cape Province, South Africa. The precise molecular events associated with tumorigenesis ...