Now showing items 51-60 of 1097
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...
Sequence variation and subtyping of human and simian T-cell lymphotropic virus type I strains from South Africa
We report on the subtyping of South African primate T-cell lymphotropic virus type I (PTLV-I) strains by investigating the LTR region using sequence analysis and restriction fragment length polymorphism (RFLP) techniques. ...
Combined antiretroviral treatment initiation during hospitalization: Outcomes in south african adults
[No abstract available]
Intracytoplasmic sperm injection with testicular spermatozoa in men with azoospermia
Purpose: The aim of the study was to gain an insight into the optimal management of the infertile couple with the husband suffering from azoospermia. Methods: One hundred and forty-two intracytoplasmic sperm injection ...
Evaluating the equivalence of clomiphene citrate with and without metformin in ovulation induction in PCOS patients
Objective: To evaluate the benefit of Metfomin added to Clomiphene Citrate in a primary ovulation induction protocol in PCOS patients Design: Prospective randomised controlled study Setting: Tygerberg Academic Hospital, ...
Zona pellucida induced acrosome reaction, sperm morphology, and sperm-zona binding assessments among subfertile men
Purpose: The study aimed to evaluate the relationship between the zona pellucida induced acrosome reaction (ZIAR) and (i) percentage normal spermatozoa as well as (ii) sperm-zona pellucida binding potential among men ...
Dynamics of respiratory gas exchange during exercise after correction of congenital heart disease
In pediatric exercise testing, conventional measures of aerobic exercise function such as maximal O2 uptake or the ventilatory anaerobic threshold (VAT) use only one value for the assessment of exercise capacity. We studied ...
Relationship between Human Sperm Morphology and Acrosomal Function
Purpose: In this study, we investigated the relationship between functionality of the acrosome and sperm morphology. Methods: Acrosome reaction (AR) was separately determined in live and dead sperm and in those with normal, ...
G-protein regulation of the solubilized human zona pellucida-mediated acrosome reaction and zona pellucida binding
Purpose: The study aimed to evaluate the (i) regulatory role of G(i)- like protein during the acrosome reaction (AR) of normal sperm donors and (ii) the role of intact acrosomes during sperm-zone binding. Methods: The ...
Use of failed-fertilized oocytes for diagnostic zona binding purposes after sperm binding improvement with a modified medium
Purpose: Because the availability of prophase oocytes for zona binding testing is limited, we compared sperm binding to the zona of failed- fertilized intracytoplasmic sperm injection (ICSI) and in vitro fertilization (IVF) ...