Now showing items 41-50 of 1096
The burden of childhood tuberculosis: A public health perspective
The burden of childhood tuberculosis (TB) reflects recent transmission within a community and the level of TB control achieved within the adult (maintenance host) population. Children contribute little to the maintenance ...
Childhood tuberculosis: The hidden epidemic
[No abstract available]
Maternal HIV infection and antibody responses against vaccine-preventable diseases in uninfected infants
Context: Altered immune responses might contribute to the high morbidity and mortality observed in human immunodeficiency virus (HIV)-exposed uninfected infants. Objective: To study the association of maternal HIV infection ...
Cytokine production in patients with tuberculous pericarditis
SETTING: An academic hospital in the Western Cape, South Africa. OBJECTIVE: To evaluate cytokine production (interferon-gamma [IFN-γ], interleukin-1 [IL-1], interleukin-2 [IL-2], interleukin-6 [IL-6], interleukin-10 [IL-10], ...
Intensive short course chemotherapy in the management of tuberculous meningitis
SETTING: Short course chemotherapy for tuberculous meningitis (TBM) is advocated by several groups, but relatively few children have been so treated and followed up. METHODS: A prospective, observational study of isoniazid ...
A prospective evaluation of children under the age of 5 years living in the same household as adults with recently diagnosed pulmonary tuberculosis
SETTING: A South African suburb with a high tuberculosis incidence (>800/100 000). OBJECTIVE: To determine the prevalence of tuberculosis infection and disease in children less than 5 years of age who were in close household ...
Isoenzymes of adenosine deaminase in pleural effusions: A diagnostic tool?
SETTING: Tygerberg Hospital, an academic teaching hospital, Republic of South Africa. OBJECTIVE: To identify the adenosine deaminase (ADA) isoenzymes as a diagnostic tool for tuberculosis in pleural effusions with increased ...
Can uroflowmetry patterns in women be reliably interpreted?
Our aim was to investigate the proposition that uroflowmetry patterns can be reliably interpreted and correspond with specific urodynamic diagnoses. Uroflowmetry traces from 129 women with diagnoses of either genuine stress ...
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa
Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...
Virologic failure and second-line antiretroviral therapy in children in South Africa-the IeDEA Southern Africa collaboration
Background: With expanding pediatric antiretroviral therapy (ART) access, children will begin to experience treatment failure and require second-line therapy. We evaluated the probability and determinants of virologic ...