Now showing items 31-40 of 655
Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007
Objective: Little is known about the temporal impact of the rapid scale-up of large antiretroviral therapy (ART) services on programme outcomes. We describe patient outcomes [mortality, loss-to-follow-up (LTFU) and retention] ...
Influence of ethnic and geographic factors on the classic photoparoxysmal response in the electroencephalogram of epilepsy patients
The classic photoparoxysmal response (CPPR) on photic stimulation in the electroencephalogram (EEG) of 128 patients with chronic epilepsy, constituting three different ethnic groups, was investigated. All patients were ...
Shigellosis in the south-western Cape of Good Hope 1968-85
During the period 1968-85 shigella organisms were isolated from stool specimens of 1562 patients attending Tygerberg Hospital, situated in the south-western province of the Cape of Good Hope of the Republic of South Africa. ...
Cervical cytology in menopausal women at high risk for endometrial disease
The objective of this study was to evaluate the value of cervical cytology in the diagnosis of endometrial disease in women after menopause. In 128 consecutive menopausal women presenting with uterine bleeding (116) or in ...
Phase II trial of ZD0473 as second-line therapy in mesothelioma
A phase II, open-label, non-comparative, multicentre trial of the platinum analogue ZD0473 as second-line therapy for pleural mesothelioma has been completed. The objectives were to evaluate the activity and tolerability ...
Esomeprazole 40 mg administered intravenously has similar safety and efficacy profiles to the oral formulation in patients with erosive esophagitis
Background/Aims: An intravenous formulation of esomeprazole has been developed for use in patients where oral administration is not appropriate. This study evaluated safety after 1 and 4 weeks, and efficacy after 4 weeks' ...
An intrapericardial hernia
[No abstract available]
Pharmacodynamic equivalence of a decapeptyl 3-month SR formulation with the 28-day SR formulation in patients with advanced prostate cancer
Aims: The objective of the study was to assess the pharmacodynamic equivalence of LHRH analogue triptorelin 3-month and 28-day SR formulations. Methods: Patients with documented locally advanced or metastatic prostate ...
An atropine and glycopyrrolate combination reduces mortality in organophosphate poisoning
Anticholinergics are the mainstay of the pharmacological management of organophosphate poisoning (OPP). Atropine has the potential to cause central toxicity which may complicate the management of this life-threatening ...
A study of semen parameters with emphasis on sperm morphology in a fertile population: An attempt to develop clinical thresholds
The aim of the study was to determine the semen parameters of a proven fertile population and to compare these parameters with that of a subfertile group in the same region. Sixty-nine fertile male patients were studied ...