Now showing items 31-40 of 240
Valvular heart disease associated with systemic lupus erythematosus - The tygerberg hospital experience
Background. Valvular heart disease is the most important cardiac manifestation of systemic lupus erythematosus (SLE). We performed a study to determine the presence of valvular heart disease in our patients with SLE. ...
Accuracy of pleural puncture sites: A prospective comparison of clinical examination with ultrasound
Study objective: To assess the value of chest ultrasonography vs clinical examination for planning of diagnostic pleurocentesis (DPC). Design: Prospective comparative study. Setting: Pulmonary unit of a tertiary teaching ...
Transbronchial needle aspirates: Comparison of two preparation methods
Study objectives: Transbronchial needle aspiration has evolved as a key bronchoscopic sampling method. Specimen handling and preparation are underrated yet crucial aspects of the technique. This study was designed to ...
Triptorelin 6-month formulation in the management of patients with locally advanced and metastatic prostate cancer: An open-label, non-comparative, multicentre, phase III study
Background and Objectives: Triptorelin 6-month formulation was developed to offer greater convenience to both patients and physicians by reducing the injection frequency. The efficacy, pharmacokinetics and safety of a new ...
Review of the prevalence of macroprolactinaemia in a South African hospital
[No abstract available]
An unusual presentation of an anomalous left coronary artery arising from the pulmonary artery (ALCAPA) in an adult: Anterior papillary muscle rupture causing severe mitral regurgitation
We describe a 29-year-old male, previously in good health, with no history of angina pectoris and no risk factors for ischemic heart disease presenting with biventricular failure and severe mitral valve regurgitation. There ...
Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study
Telavancin is a bactericidal lipoglycopeptide with a multifunctional mechanism of action. We conducted a randomized, double blind, active-control phase II trial. Patients S18 years of age with complicated skin and skin ...
Long-Term Efficacy and Safety of Rosuvastatin 40 mg in Patients With Severe Hypercholesterolemia
Patients with elevated low-density lipoprotein (LDL) cholesteral levels are at high risk of cardiovascular events but are often undertreated and fail to achieve lipid goals. This open-label, noncomparative, multicenter ...
Intragastric pH during Continuous Infusion with Pantoprazole in Patients with Bleeding Peptic Ulcer
OBJECTIVES: In managing patients with bleeding peptic ulcers, prevention of rebleeding is a particular challenge to hemostasis and fibrinolysis, both of which involve reactions that are impaired in acidic gastric environment. ...
Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin
OBJECTIVES: Low-dose aspirin is standard treatment for prevention of cardiovascular events in at-risk patients. However, long-term administration of low-dose aspirin is associated with a greater risk of adverse events, ...