Now showing items 31-40 of 107
Placental histology related to fetal brain sonography
Background: Chronic hypoxia and inflammatory processes can induce placental disturbances that may indirectly lead to perinatal brain injury. Objective: To study histological features of the placenta in relation to echogenicity ...
An investigation into LOXL1 variants in black South African individuals with exfoliation syndrome
Objective: To investigate the association between 2 lysyl oxidase-like 1 (LOXL1) polymorphisms, rs1048661 (R141L) and rs3825942 (G153D), and exfoliation syndrome (XFS) in black South African individuals. Methods: A total ...
Clinical significance of the low normal sperm morphology value as proposed in the fifth edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen
The very low cut-off value for sperm morphology of 4% morphologically normal spermatozoa, as proposed in the new edition of the World Health Organization (WHO) manual on semen analysis, is in agreement with recently published ...
Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk
Although inflammation is emerging as a candidate prostate cancer risk factor, the T-helper cytokine-rich [interleukins (IL)-5, 13 and 4] chromosomal region at 5q31.1 has been implicated in prostate cancer pathogenesis. In ...
A South African national database in cardiothoracic surgery
This article aims to update South African cardiothoracic surgeons on the developmental progress of the national database in cardiac and thoracic surgery and to encourage participation in this most important endeavour.
The growing disparity between clinical trial complexity and investigator compensation
[No abstract available]
The S/Z ratio: A simple and reliable clinical method of evaluating laryngeal function in patients after intubation
Objectives: 1. To determine the consequences of prolonged intubation on laryngeal function.2. To evaluate simple clinical criteria or tests that could alert the clinician to potential laryngeal pathology requiring ear, ...
A Six Sigma approach to the rate and clinical effect of registration errors in a laboratory
Background: Laboratory errors made during the preanalytical phase can have an impact on clinical care. Quality management tools such as Six Sigma may help improve error rates. Aim: To use elements of a Six Sigma model to ...
Tuberculous meningitis-related optic neuritis: Recovery of vision with thalidomide in 4 consecutive cases
Blindness is an uncommon but devastating complication of tuberculosis meningitis. The main causes are chronically raised intracranial pressure (hydrocephalus and/or tuberculomas) or direct involvement of the optic chiasm ...