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The association between the antiphospholipid antibody syndrome and neuropsychological impairment in SLE

Whitelaw D.A.; Spangenberg J.J.; Rickman R.; Hugo F.H.; Roberts M. (1999)

Objective: To examine the relationship between neuropsychological impairment and antiphospholipid antibody syndrome (aPL syndrome) in patients with systemic lupus erythermatosus (SLE). Patients: Sixty-nine patients satisfying ...

rhuIL-2 adjunctive therapy in multidrug resistant tuberculosis: A comparison of two treatment regimens and placebo

Johnson B.J.; Bekker L.-G.; Rickman R.; Brown S.; Lesser M.; Ress S.; Willcox P.; Steyn L.; Kaplan G. (1997)

Setting: Low-dose recombinant human interleukin 2 (rhuIL-2) adjunctive immunotherapy in multidrug resistant tuberculosis (MDR-TB) patients. Objective: Evaluation of the effects of daily versus pulse-administered rhuIL-2 ...

Detection and subtyping of human herpesvirus-8 in renal transplant patients before and after remission of Kaposi's sarcoma

Moosa M.R.; Treurnicht F.K.; Van Rensbubg E.J.; Schneider J.W.; Jordaan H.F.; Engelbrecht S. (1998)

Background. Kaposi's sarcoma (KS) is a complication of renal transplantation. If the human herpesvirus-8 (HHV-8) causes KS, the virus should be present in all KS lesions and be drastically reduced or cleared from involved ...

Inositol augmentation of serotonin reuptake inhibitors in treatment-refractory obsessive - compulsive disorder: An open trial

Seedat S.; Stein D.J. (1999)

Inositol, an isomer of glucose and precursor in the phosphatidylinositol cycle, may be effective in a number of psychiatric disorders, including obsessive - compulsive disorder (OCD). There is little data, however, on ...

Phasic craving for carbohydrate observed with citalopram

Bouwer C.D.; Harvey B.H. (1996)

The serotonin selective reuptake inhibitors (SSRIs) have clinically and ancedotally been associated with nausea and weight loss as a side effect of their action. The tricyclic antidepressants have been linked to carbohydrate ...

Mutation analysis reveals an insertional hotspot in exon 4 of the LDL receptor gene

Kotze M.J.; Thiart R.; Loubser O.; De Villiers J.N.P.; Santos M.; Vargas M.A.; Peeters A.V. (1996)

Mutation analysis of the low density lipoprotein receptor (LDLR) gene revealed a novel 8-bp duplication after nucleotide 681 in a Costa Rican patient with familial hypercholesterolaemia. The frameshift caused by this ...

p53 and p16/CDKN2 gene mutations in esophageal tumors from a high- incidence area in South Africa

Gamieldien W.; Victor T.C.; Mugwanya D.; Stepien A.; Gelderblom W.C.A.; Marasas W.F.O.; Geiger D.H.; Van Helden P.D. (1998)

Squamous cell carcinoma of the esophagus has an uneven geographic distribution, with a high incidence in the Transkei region of Eastern Cape Province, South Africa. The precise molecular events associated with tumorigenesis ...

Depressive and anxiety symptoms in patients with schizophrenia and schizophreniform disorder

Emsley R.A.; Oosthuizen P.P.; Joubert A.F.; Roberts M.C.; Stein D.J. (1999)

Background: Symptoms of depression and anxiety are frequently encountered in the course of schizophrenia and are of considerable clinical importance. They may compromise social and vocational functioning, and they are ...

Transmission of a multidrug-resistant Mycobacterium tuberculosis strain resembling 'strain W' among noninstitutionalized, human immunodeficiency virus-seronegative patients

Van Annelies R.; Warren R.M.; Beyers N.; Gie R.P.; Classen C.N.; Richardson M.; Sampson S.L.; Victor T.C.; Van Helden P.D. (1999)

Since 1990, several outbreaks of multidrug-resistant tuberculosis (MDR- TB) have been described among institutionalized patients infected with human immunodeficiency virus (HIV). We describe a community MDR-TB outbreak ...