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Now showing items 1-9 of 9

Evaluating the BED capture enzyme immunoassay to estimate HIV incidence among adults in three countries in sub-Saharan Africa

Kim, A. A.; McDougal, J. S.; Hargrove, J.; Rehle, T.; Pillay-Van Wyk, V.; Puren, A.; Ekra, A.; Borget-Alloue, M. Y.; Adje-Toure, C.; Abdullahi, A. S.; Odawo, L.; Marum, L.; Parekh, B. S. (2010)

Serological assays for estimating HIV-1 incidence are prone to misclassification, limiting the accuracy of the incidence estimate. Adjustment factors have been developed and recommended for estimating assay-based HIV-1 ...

Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa

Fenner L.; Brinkhof M.W.G.; Keiser O.; Weigel R.; Cornell M.; Moultrie H.; Prozesky H.; Technau K.; Eley B.; Vaz P.; Pascoe M.; Giddy J.; Van Cutsem G.; Wood R.; Egger M.; Davies M.-A. (2010)

Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...

Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid

Cilliers K.; Labadarios D.; Schaaf H.S.; Willemse M.; Maritz J.S.; Werely C.J.; Hussey G.; Donald P.R. (2010)

Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...

Temporal changes in programme outcomes among adult patients initiating antiretroviral therapy across South Africa, 2002-2007

Cornell M.; Grimsrud A.; Fairall L.; Fox M.P.; Van Cutsem G.; Giddy J.; Wood R.; Prozesky H.; Mohapi L.; Graber C.; Egger M.; Boulle A.; Myer L. (2010)

Objective: Little is known about the temporal impact of the rapid scale-up of large antiretroviral therapy (ART) services on programme outcomes. We describe patient outcomes [mortality, loss-to-follow-up (LTFU) and retention] ...

Evaluation of paradoxical TB-associated IRIS with the use of standardized case definitions for resource-limited settings

Eshun-Wilson I.; Havers F.; Nachega J.B.; Prozesky H.W.; Taljaard J.J.; Zeier M.D.; Cotton M.; Simon G.; Soentjens P. (2010)

Objective: Standardized case definitions have recently been proposed by the International Network for the Study of HIV-associated immune reconstitution inflammatory syndrome (INSHI; [IRIS]) for use in resource-limited ...

Inhibitors and facilitators of willingness to participate (WTP) in an HIV vaccine trial: Construction and initial validation of the Inhibitors and Facilitators of Willingness to Participate Scale (WPS) among women at risk for HIV infection

Fincham D.; Kagee A.; Swartz L. (2010)

A psychometric scale assessing inhibitors and facilitators of willingness to participate (WTP) in an HIV vaccine trial has not yet been developed. This study aimed to construct and derive the exploratory factor structure ...

Positive futures: A qualitative study on the needs of adolescents on antiretroviral therapy in South Africa

Li R.J.; Jaspan H.B.; O'Brien V.; Rabie H.; Cotton M.F.; Nattrass N. (2010)

With the increasing availability of highly active antiretroviral therapy, vertically infected children have a better chance of surviving into adolescence and adulthood. Additionally, sexual transmission of human immunodeficiency ...

Renal manifestations in children co-infected with HIV and disseminated tuberculosis

Nourse P.J.; Cotton M.F.; Bates W.D. (2010)

Many children in Cape Town are co-infected with human immunodeficiency virus (HIV) and tuberculosis (TB). Granulomatous TB interstitial nephritis is a recognized entity. Our objective was to establish if TB plays a role ...

Characterization of HIV type 1 genetic diversity among South African participants enrolled in the AIDS Vaccine Integrated Project (AVIP) Study

Papathanasopoulos M.A.; Vardas E.; Wallis C.; Glashoff R.; Butto S.; Poli G.; Malnati M.; Clerici M.; Ensoli B. (2010)

The genetic diversity of HIV-1 strains circulating among HIV-1-infected South Africans was investigated in a cohort of 420 individuals enrolled as part of the AIDS Vaccine Integrated Project (AVIP) study. Representative ...