Now showing items 1-10 of 31
Evaluating the BED capture enzyme immunoassay to estimate HIV incidence among adults in three countries in sub-Saharan Africa
Serological assays for estimating HIV-1 incidence are prone to misclassification, limiting the accuracy of the incidence estimate. Adjustment factors have been developed and recommended for estimating assay-based HIV-1 ...
Interferon-gamma release assays for the detection of Mycobacterium tuberculosis infection in children with cancer
SETTING: The paediatric oncology unit at Tygerberg Children's Hospital, South Africa. OBJECTIVES: To assess the use of the tuberculin skin test (TST) and two commercial interferon-gamma release assays (IGRAs) for the ...
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa
Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
Radiological changes post-lymph node enucleation for airway obstruction in children with pulmonary tuberculosis
Background: Tuberculous lymphadenopathy causing airway obstruction in children may be life threatening and may require surgical enucleation of the lymph glands. There are no studies investigating the radiological picture ...
HIV prevention through sport: The case of the Mathare Youth Sport Association in Kenya
Sport has become a popular tool for HIV prevention, based on claims that it can foster life skills that are necessary to translate knowledge, attitudes and behavioural intentions into actual behaviour. Empirical evidence ...
Granular myringitis: Report of three prospective studies evaluating treatment options
[No abstract available]
Comparison of two active case-finding strategies for community-based diagnosis of symptomatic smear-positive tuberculosis and control of infectious tuberculosis in Harare, Zimbabwe (DETECTB): A cluster-randomised trial
Background Control of tuberculosis in settings with high HIV prevalence is a pressing public health priority. We tested two active case-finding strategies to target long periods of infectiousness before diagnosis, which ...
Psychological distress among persons living with HIV, hypertension, and diabetes
It has been assumed that receipt of a diagnosis of HIV is a uniquely distressing event, more so than with any other illness. The present study compared the mean scores on the Hopkins Symptom Checklist, a measure of emotional ...
Iron status in children with recurrent episodes of tumefactive cerebral demyelination
Iron is a vital element in the multifactorial initiation of myelination. It is required for cholesterol and lipid biosynthesis, both key components of myelin. Iron also plays an important role in energy production by ...