Now showing items 1-10 of 38
Evaluating the BED capture enzyme immunoassay to estimate HIV incidence among adults in three countries in sub-Saharan Africa
Serological assays for estimating HIV-1 incidence are prone to misclassification, limiting the accuracy of the incidence estimate. Adjustment factors have been developed and recommended for estimating assay-based HIV-1 ...
An intrapericardial hernia
[No abstract available]
Comparison of two active case-finding strategies for community-based diagnosis of symptomatic smear-positive tuberculosis and control of infectious tuberculosis in Harare, Zimbabwe (DETECTB): A cluster-randomised trial
Background Control of tuberculosis in settings with high HIV prevalence is a pressing public health priority. We tested two active case-finding strategies to target long periods of infectiousness before diagnosis, which ...
Psychological distress among persons living with HIV, hypertension, and diabetes
It has been assumed that receipt of a diagnosis of HIV is a uniquely distressing event, more so than with any other illness. The present study compared the mean scores on the Hopkins Symptom Checklist, a measure of emotional ...
Rapid on-site evaluation of transbronchial aspirates: Randomised comparison of two methods
The value of different staining methods for rapid analysis of transbronchial needle aspirates during bronchoscopy has not been explored. In the present study, we compared a Papanicolaou-based rapid stain, prepared by a ...
Monoclonal gammopathy and other serum protein electrophoresis patterns in patients with HIV infection in South Africa
Background: Monoclonal gammopathy has been noted with increased frequency in patients with HIV infection compared with the general population. The prevalence in patients on antiretroviral therapy (ART) has not been widely ...
Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk
Although inflammation is emerging as a candidate prostate cancer risk factor, the T-helper cytokine-rich [interleukins (IL)-5, 13 and 4] chromosomal region at 5q31.1 has been implicated in prostate cancer pathogenesis. In ...
Evaluation of paradoxical TB-associated IRIS with the use of standardized case definitions for resource-limited settings
Objective: Standardized case definitions have recently been proposed by the International Network for the Study of HIV-associated immune reconstitution inflammatory syndrome (INSHI; [IRIS]) for use in resource-limited ...