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Low-dose stavudine trials: a public health priority for developing countries
Venter, W. D. Francois ; Innes, Steve ; Cotton, Mark (2012-03-13)
CITATION: Venter, W. D. F., Innes, S. & Cotton, M. 2012. Low-dose stavudine trials: a public health priority for developing countries. South African Journal of HIV Medicine, 13(1):20-21, doi: 10.4102/sajhivmed.v13i1.154.
The original publication is available at http://www.sajhivmed.org.za
The debate around relooking at stavudine dosing, both in terms of the adult low-dose stavudine study and more broadly, is welcome. The study being proposed to evaluate low-dose stavudine v. tenofovir is a fairly standard placebo-controlled non-inferiority study. The study design is not controversial; however, the choice of study drug has attracted critical attention.