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High prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing : a cross-sectional population based sero-survey in South Africa

dc.contributor.authorKranzer, Katharinaen_ZA
dc.contributor.authorVan Schaik, Nienkeen_ZA
dc.contributor.authorKarmue, Uniceen_ZA
dc.contributor.authorMiddelkoop, Kerenen_ZA
dc.contributor.authorSebastian, Elaineen_ZA
dc.contributor.authorLawn, Stephen D.en_ZA
dc.contributor.authorWood, Robiinen_ZA
dc.contributor.authorBekker, Linda-Gailen_ZA
dc.date.accessioned2012-01-18T08:06:27Z
dc.date.available2012-01-18T08:06:27Z
dc.date.issued2011-09-28
dc.identifier.citationKranzer, K. et al. 2011. High prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing : a cross-sectional population based sero-survey in South Africa. PLoS ONE, 6(9): e25244, doi:10.1371/journal.pone.0025244.
dc.identifier.issn1932-6203 (online)
dc.identifier.otherdoi:10.1371/journal.pone.0025244
dc.identifier.urihttp://hdl.handle.net/10019.1/18980
dc.descriptionCITATION: Kranzer, K. et al. 2011. High prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing : a cross-sectional population based sero-survey in South Africa. PLoS ONE, 6(9): e25244, doi:10.1371/journal.pone.0025244.
dc.descriptionThe original publication is available at http://journals.plos.org/plosone
dc.description.abstractObjectives To measure HIV prevalence and uptake of HIV counseling and testing (HCT) in a peri-urban South African community. To assess predictors for previous HIV testing and the association between the yield of previously undiagnosed HIV and time of last negative HIV test Methods A random sample of 10% of the adult population (≥15 years) were invited to attend a mobile HCT service. Study procedures included a questionnaire, HIV testing and CD4 counts. Predictors for previous testing were determined using a binominal model. Results 1,144 (88.0%) of 1,300 randomly selected individuals participated in the study. 71.0% (68.3–73.6) had previously had an HIV test and 37.5% (34.6–40.5) had tested in the past 12 months. Men, migrants and older (>35 years) and younger (<20 years) individuals were less likely to have had a previous HIV test. Overall HIV prevalence was 22.7 (20.3–25.3) with peak prevalence of 41.8% (35.8–47.8) in women aged 25.1–35 years and 37.5% (26.7–48.3) in men aged 25.1–45 years. Prevalence of previously undiagnosed HIV was 10.3% (8.5–12.1) overall and 4.5% (2.3–6.6), 8.0% (CI 3.9–12.0) and 20.0% (13.2–26.8) in individuals who had their most recent HIV test within 1, 1–2 and more than 2 years prior to the survey. Conclusion The high burden of undiagnosed HIV in individuals who had recently tested underscores the importance of frequent repeat testing at least annually. The high prevalence of previously undiagnosed HIV in individuals reporting a negative test in the 12 months preceding the survey indicates a very high incidence. Innovative prevention strategies are needed.
dc.description.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0025244
dc.format.extent6 pages
dc.publisherPublic Library of Science
dc.subjectHIV infections -- South Africaen_ZA
dc.subjectHIV infections -- Diagnosisen_ZA
dc.titleHigh prevalence of self-reported undiagnosed HIV despite high coverage of HIV testing : a cross-sectional population based sero-survey in South Africaen_ZA
dc.typeArticle
dc.description.versionPublisher's version
dc.rights.holderAuthors retain copyright


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