Now showing items 1-5 of 5
Elucidation of the substrates of mycosin 3, an essential protease of Mycobacterium tuberculosis
(Stellenbosch : University of Stellenbosch, 2011-03)
ENGLISH ABSTRACT: Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), infects one third of the world’s population and kills 1.7 million people per year. The increasing prevalence of multi- and extensively ...
Genetic investigations of pneumocystis jirovecii : detection, cotrimoxazole resistance and population structure
(Stellenbosch : University of Stellenbosch, 2005-12)
Pneumocystis jirovecii is a significant contributor to the burden of disease in immunocompromised patients. The polymerase chain reaction (PCR) is more sensitive and specific than microscopy. Cotrimoxazole prophylactic ...
Enzyme-linked immunosorbent assay for the detection of mycobacterial antigens in the cerebrospinal fluid in tuberculous meningitis
(Health & Medical Publishing Group, 1987)
Fifty-three cerebrospinal fluid specimens from meningitis patients were investigated by enzyme-linked immunosorbent assay for detection of mycobacterial antigens. After heating at 56° C for 1 hour to eliminate nonspecific ...
Susceptibility of a series of routine sputum samples for antituberculosis chemotherapy in Gweru, Zimbabwe
(Health & Medical Publishing Group, 2004)
Resistance of Mycobacterium tuberculosis to the commonly used antibiotics in national tuberculosis programmes (NTPs) is a growing concern in many parts of the world.1 Nevertheless there is much anecdotal, but ...
Development of functional immune readouts for the confirmation of mendelian susceptibility to mycobacterial disease and related primary immunodeficiencies
(Stellenbosch : Stellenbosch University, 2019-04)
Background: Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a primary immunodeficiency (PID) characterised by a predisposition to infection by weakly-pathogenic mycobacteria. In countries with a high prevalence ...