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Longitudinal investigation of vaccine specific antibody levels and cellular markers of adaptive immune responses in HIV Exposed Uninfected (HEU) and Unexposed (UE) infants
(Stellenbosch : Stellenbosch University, 2012-03)
ENGLISH ABSTRACT: Background: In South Africa alone, 30% of women of child-bearing age are infected with HIV. With the increasing focus and success of prevention of mother-to-child transmission (PMTCT) programmes, an ...
Ontogeny of toll-like receptor mediated cytokine responses of South African infants throughout the first year of life
(Public Library of Science, 2012-09-13)
The first year of life represents a time of marked susceptibility to infections; this is particularly true for regions in sub-Saharan Africa. As innate immunity directs the adaptive immune response, the observed increased ...
Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life
(American Society for Microbiology, 2013-01)
HIV-exposed but uninfected (HEU) infants born to HIV-infected mothers from areas in the world with a high burden of infectious disease suffer higher infectious morbidity and mortality than their HIV unexposed uninfected ...