Search

Now showing items 1-4 of 4

Analysis of the clinical utility of gene expression profiling in relation to conventional prognostic markers in South African patients with breast carcinoma

Grant, Kathleen Ann (Stellenbosch : Stellenbosch University, 2014-12)

ENGLISH ABSTRACT: Breast cancer is a heterogeneous disease characterised by marked inter-individual variability in presentation, prognosis and clinical outcome. The recognition that morphological assessment has limited ...

An evaluation of the diagnostic adequacy and immunocytochemistry of manual liquid-based smears in breast aspirates

Shibemba, A. L.; Wright, C. A.; Bezuidenhout, J.; Schubert, P. T. (Medpharm Publications, 2013)

The aim of this study was to determine if the Syner-Med®/Cell-Solutions® liquid-based cytology (LBC) technique would provide adequate diagnostic material when applied to breast fine-needle aspiration biopsy (FNAB) specimens ...

Exome sequencing in a family with luminal-type breast cancer underpinned by variation in the methylation pathway

Van der Merwe, Nicole; Peeters, Armand V.; Pienaar, Fredrieka M.; Bezuidenhout, Juanita; Van Rensburg, Susan J.; Kotze, Maritha J. (MDPI, 2017-02-22)

ENGLISH ABSTRACT: Panel-based next generation sequencing (NGS) is currently preferred over whole exome sequencing (WES) for diagnosis of familial breast cancer, due to interpretation challenges caused by variants of uncertain ...

Chemotherapy naive breast cancer: a correlation study between BD Cytorich™ Red cell blocks and formalin- fixed paraffinembedded tissue blocks

Van Rooyen, Evelyn (Stellenbosch : Stellenbosch University, 2019-04)

Background: The ever increasing burden of breast cancer, the most common cancer among women, demands a diagnostic test that is rapid, reliable, informative and cost-effective; particularly in countries with limited ...