Operational challenges in managing Isoniazid Preventive Therapy in child contacts : a high-burden setting perspective

Van Wyk, Susan S. ; Reid, Anthony J. ; Mandalakas, Anna M. ; Enarson, Donald A. ; Beyers, Nulda ; Morrison, Julie ; Hesseling, Anneke C. (2011-07-08)

The original publication is available at http://www.biomedcentral.com/1471-2458/11/544


Abstract Background The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. Methods This study was a record review of routinely-collected programme data. Results A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. Conclusions IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/16294
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