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Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ
(2014-10)
Corticosteroid-binding globulin (CBG), a negative acute phase protein produced primarily in the liver, is responsible for the transport of glucocorticoids (GCs). It also modulates the bioavailability of GCs, as only free ...
Sutherlandia frutescens may exacerbate HIV-associated neuroinflammation
(BioMed Central, 2015-07-18)
Background: Neuroinflammation is central to the aetiology of HIV-associated neurocognitive disorders (HAND) that
are prevalent in late stage AIDS. Anti-retroviral (ARV) treatments are rolled out relatively late in the ...
Ageing-associated oxidative stress and inflammation are alleviated by products from grapes
(Hindawi, 2016)
Advanced age is associated with increased incidence of a variety of chronic disease states which share oxidative stress and
inflammation as causative role players. Furthermore, data point to a role for both cumulative ...
Exercise, stress and immune system functional responses
(Stellenbosch : University of Stellenbosch, 2004-12)
ENGLISH ABSTRACT: Stress related to chronic exercise affects both the immune and endocrine systems, but there
are still many issues that are poorly understood, particularly effects of stress on the
functional capacity ...
Endocrine and immune effects of dexamethasone in unilateral total knee replacement
(SAGE Publications, 2006)
The effect of acute pre-surgery dexamethasone treatment on the inflammatory immune and endocrine responses to orthopaedic surgery was investigated. Whole blood samples were obtained before and 5 days after surgery for ...
Gender differences in metabolic risk factor prevalence in a South African student population
(Clinics Cardiv Publishing, 2009-06)
We determined selected risk factors for the metabolic
syndrome and assessed the metabolic risk status (using IDF
criteria) of third-year physiology students at Stellenbosch
University (88 males and 178 females). Outcome ...
Interplay of the inflammatory and stress systems in a hepatic cell line : interactions between glucocorticoid receptor agonists and interleukin-6
(HighWire Press, 2010-11)
The liver plays an important role in inflammation and stress by producing the acute phase proteins
(APPs) required for resolution of inflammation as well as by delivering systemic glucose, through
gluconeogenesis, required ...
Using rodent models to simulate stress of physiologically relevant severity : when, why and how
(InTech, Rijeka, Croatia, 2012)
Given the demands of modern life, it is no wonder that the concept of stress has become a
household topic for discussion. Also in the academic realm the phenomenon which is stress,
is topping the charts in terms of ...
Influence of lifestyle choices on metabolic risk has distinct gender and age differences
(Medknow Publications, 2014)
Background and Aim: We aimed to determine the incidence of metabolic syndrome risk factors in young and older university
campus population. The infl uence of life-style choices on the physiological risk profi le was also ...
Harnessing Macrophages for Controlled-Release Drug Delivery : lessons From Microbes
(Frontiers Media, 2019)
With the effectiveness of therapeutic agents ever decreasing and the increased incidence of multi-drug resistant pathogens, there is a clear need for administration of more potent, potentially more toxic, drugs. Alternatively, ...