Department of Medical Imaging and Clinical Oncology: Recent submissions
Now showing items 1-20 of 173
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Automated radiation treatment planning for cervical cancer
(Elsevier, 2020-10)The radiation treatment-planning process includes contouring, planning, and reviewing the final plan, and each component requires substantial time and effort from multiple experts. Automation of treatment planning can save ... -
Mammography reporting at Tygerberg Hospital, Cape Town, South Africa
(Health & Medical Publishing Group, 2014-07)In their recent article, Apffelstaedt et al.[1] analysed 16 105 mammograms performed at Tygerberg Hospital (TBH), Cape Town, South Africa (SA), between 2003 and 2012. The summary reported that ‘mammograms were read by ... -
A multi-institutional quantitative survey of multi-leaf collimator accuracy using a digital picket fence test with sub-millimetre detection capabilities.
(Stellenbosch : Stellenbosch University, 2022-04)ENGLISH SUMMARY: When patients are treated with modern radiotherapy, multi-leaf collimators (MLC) are used to shape treatment fields. With recent advances in technology, MLCs have also been used to modulate dose in certain ... -
Towards equity : a retrospective analysis of public sector radiological resources and utilization patterns in the metropolitan and rural areas of the Western Cape Province of South Africa in 2017
(BMC (part of Springer Nature), 2021)Background: The reduction of inequality is a key United Nations 2030 Sustainable Development Goal (WHO, Human Resources for Health: foundation for Universal Health Coverage and the post-2015 development agenda, 2014; ... -
Fully automatic treatment planning for external-beam radiation therapy of locally advanced cervical cancer : a tool for low-resource clinics
(American Society of Clinical Oncology, 2019)PURPOSE: The purpose of this study was to validate a fully automatic treatment planning system for conventional radiotherapy of cervical cancer. This system was developed to mitigate staff shortages in low-resource ... -
Evaluation of BCL-2 and PARP-1 as potential therapeutic targets to radiosensitise lung cancer
(Stellenbosch : Stellenbosch University, 2021-12)ENGLISH SUMMARY : Lung cancer remains the most incident malignancy worldwide, representing 13% of all cancers. It is also the leading cause of death in the world, accounting for 18 18.2% of global cancer-related deaths. ... -
Dual energy window imaging for optimisation of P/V ratios in VP SPECT
(SpringerOpen, 2021)Purpose: Ventilation–perfusion single-photon emission computed tomography (VP SPECT) plays an important role in pulmonary embolism diagnosis. Rapid results may be obtained using same-day ventilation followed by perfusion ... -
An audit of licensed Zimbabwean radiology equipment resources as a measure of healthcare access and equity
(Pan African Medical Journal, 2019-10-01)Introduction: approximately two-thirds of the world's population has no access to diagnostic imaging. Basic radiological services should be integral to universal health coverage. The World Health Organization postulates ... -
A risk assessment of automated treatment planning and recommendations for clinical deployment
(American Association of Physicists in Medicine, 2019-06)Purpose: To assess the risk of failure of a recently developed automated treatment planning tool, the radiation planning assistant (RPA), and to determine the reduction in these risks with implementation of a quality ... -
Automated treatment planning of postmastectomy radiotherapy
(American Association of Physicists in Medicine, 2019-05-11)Purpose: Breast cancer is the most common cancer in women globally and radiation therapy is a cornerstone of its treatment. However, there is an enormous shortage of radiotherapy staff, especially in low- and middle-income ... -
The utility of PET-CT in the staging and management of advanced and recurrent malignant melanoma
(Medpharm Publications, 2019)BACKGROUND: Accurate pre-operative staging and correct surgical selection of patients with malignant melanoma reduces unnecessary morbidity and mortality, improves distant control and may improve survival. 18F-fluorodeoxyglucose ... -
Semiquantitative analysis of FDG PET brain scans using Neurostat and SPM
(Stellenbosch : Stellenbosch University, 2021-12)ENGLISH SUMMARY : Background: Positron emission tomography using Fluorine-18 2-Fluoro-2-Deoxy-D-Glucose (FDG-PET) has an established role in the investigation of multiple neurological conditions such as neurolupus and ... -
Peptide receptor radionuclide therapy of neuroendocrine tumors : how important is internal dosimetry?
(Health and Medical Publishing Group, 2019)No abstract available -
Advanced radiological investigations and findings amongst community assault victims admitted to a tertiary South African hospital
(Health and Medical Publishing Group, 2019)Community assault (CA) has been increasing in certain Cape Town suburbs over the past decade. There are limited CA-related imaging data. The aim of this study was to review CA-related advanced radiological investigations ... -
Managing gestational trophoblastic neoplasm (GTN) and people living with HIV (PLWH)
(MedPharm Publications, 2019)The 2017 World Health Organization (WHO) global report on HIV/AIDS estimated that sub-Saharan Africa comprised 64% of the global HIV burden, with a current estimate of 19.4 million cases in Eastern and Southern Africa. ... -
Influence of acquisition time and smoothing parameters on Ga-68 wholebody PET/CT image quality
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH SUMMARY : PET/CT image optimization has been extensively investigated for 18F–FDG PET imaging. Although 68Ga–tracers are already widely used in PET, optimized imaging and reconstruction are still missing. The aim ... -
Optimization of production methods for gallium-68 PET radiopharmaceuticals in a hospital radiopharmacy
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH SUMMARY : Production of radiopharmaceuticals intended for human use and research purposes is generally performed in well-equipped commercial or research facilities that usually have access to advanced equipment for ... -
Implementation of guidelines on hospital radiopharmacy in low-income settings
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH SUMMARY : Although radiopharmacy is more than 50 years old, it is still in a stage of rapid development. This dissertation focuses on quality issues in radiopharmacies in developing countries. Guidelines for ... -
Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments
(BMC (part of Springer Nature), 2020-05-19)Background: Perinatal HIV infection negatively impacts cognitive functioning of children, main domains affected are working memory, processing speed and executive function. Early ART, even when interrupted, improves ... -
Validation of a cost-effective alternative for a radiochromatography method to be used in a developing country
(SpringerOpen (part of Springer Nature), 2020-04-10)Introduction: The radiochemical purity (RCP) of technetium-99m labelled radiopharmaceuticals (RP) is important to ensure optimal scintigraphic image quality. In low-income settings, it may not be possible to use compendial ...
