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Monitoring various eluate characteristics of the iThemba LABS SnO2-based 68Ge/68Ga generator over time and validation of quality control methods for the radiochemical purity assessment of 68Ga-labelled DOTA peptide formulations
(Stellenbosch : Stellenbosch University, 2017-03)
ENGLISH SUMMARY : PET imaging with gallium-68 (68Ga) has become widely used due to the availability of 68Ge/68Ga generators and DOTA-derivatised peptide ligands for radiolabelling. The purpose of this study was to monitor ...
The value of different reconstruction algorithms for quantification of FDG PET brain imaging
(Stellenbosch : Stellenbosch University, 2016-12)
ENGLISH SUMMARY : Modern reconstruction techniques of positron emission tomography/computed tomography (PET/CT) data are optimized for whole body imaging. Such optimization is less developed for brain imaging. This study ...
An investigation of the contribution of Single Photon Emission Computed Tomography to the diagnosis of skeletal metastases using bone scan in the African context
(Stellenbosch : Stellenbosch University, 2003-12)
ENGLISH ABSTRACT: Planar bone scintigraphy is highly sensitive but it may not be sensitive enough
to detect subtle lesions in complex bony structures such as the spine. The
accurate anatomic localisation of lesions in ...
Investigation into various aspects of radiolabelling somatostatin peptide derivatives with 68Ga eluted from a SnO2-based 68Ge/68Ga generator
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH SUMMARY : 68Ge/68Ga generators ensure the supply of 68Ga for positron emission tomography (PET), for instance for somatostatin receptor imaging with 68Ga-DOTA-labelled somatostatin analogues. There are
various ...
Appropriate indications for positron emission tomography/computed tomography : College of Nuclear Physicians of the Colleges of Medicine of South Africa
(Health & Medical Publishing Group, 2016)
Individualised patient treatment approaches demand precise determination of initial disease extent combined with early, accurate assessment of response to treatment, which is made possible by positron emission tomography/computed ...
The utility of PET-CT in the staging and management of advanced and recurrent malignant melanoma
(Medpharm Publications, 2019)
BACKGROUND: Accurate pre-operative staging and correct surgical selection of patients with malignant melanoma reduces unnecessary morbidity and mortality, improves distant control and may improve survival. 18F-fluorodeoxyglucose ...
Semiquantitative analysis of FDG PET brain scans using Neurostat and SPM
(Stellenbosch : Stellenbosch University, 2021-12)
ENGLISH SUMMARY : Background: Positron emission tomography using Fluorine-18 2-Fluoro-2-Deoxy-D-Glucose (FDG-PET) has an established role in the investigation of multiple neurological conditions such as neurolupus and ...