Use of adenosine deaminase as a diagnostic tool for tuberculous pleurisy
Date
1995
Authors
Burgess L.J.
Maritz F.J.
Le Roux I.
Taljaard J.J.F.
Journal Title
Journal ISSN
Volume Title
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Abstract
Background - A statistical audit of adenosine deaminase (ADA) in pleural effusions was undertaken. Methods - ADA analysis, cytological and microbiological examinations, and differential cell counts were performed on 462 pleural fluid samples. Results - ADA activity in tuberculous effusions was higher than in any other diagnostic group. At a level of 50 U/l the sensitivity and specificity for the identification of tuberculosis was 90% and 89%, respectively. Conclusions - ADA activity remains a useful test in the evaluation of pleural effusions.
Description
Keywords
adenosine deaminase, article, cell count, clinical trial, controlled clinical trial, controlled study, diagnostic value, enzyme activity, human, human tissue, lung tuberculosis, major clinical study, pleura effusion, priority journal, south africa, tuberculous pleurisy, Adenosine Deaminase, Adolescent, Adult, Aged, Aged, 80 and over, Biological Markers, Child, Child, Preschool, Diagnosis, Differential, Enzyme Tests, Female, Humans, Infant, Male, Medical Audit, Middle Aged, Pleural Effusion, Sensitivity and Specificity, Tuberculosis, Pleural
Citation
Thorax
50
6
50
6