Paraneoplastic bilateral proptosis in a case of non-small cell lung cancer

Date
2003
Authors
Diacon A.H.
Schuurmans M.M.
Colesky F.J.
Bolliger C.T.
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Abstract
We report the case of a 51-year-old woman with a large cell bronchial carcinoma with neuroendocrine differentiation (T3N0M0, stage IIB) and bilateral exophthalmos. A CT of the orbitae was compatible with Graves ophthalmopathy, but neither abnormalities in thyroid function nor thyroid antibodies could be found. The proptosis normalized 10 days after tumor resection. We conclude that the most likely cause of the reversible proptosis in this patient is paraneoplastic, a condition not previously described in the English-language literature.
Description
Keywords
thyroid antibody, adult, article, bronchus fistula, cancer patient, cancer surgery, case report, clinical feature, computer assisted tomography, exophthalmos, eye disease, female, Graves disease, histopathology, human, human tissue, lung non small cell cancer, lung resection, neuroendocrine disease, paraneoplastic syndrome, postoperative complication, priority journal, septic shock, Staphylococcus infection, thyroid function, treatment outcome, Carcinoma, Large Cell, Diagnosis, Differential, Exophthalmos, Female, Humans, Lung Neoplasms, Middle Aged, Neoplasm Staging, Paraneoplastic Syndromes, Tomography, X-Ray Computed
Citation
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