A critical appraisal of the clinical pharmacokinetics of isoniazid

Parkin, Donald Pysden (1996-12)

Thesis (PhD (Medicine. Pharmacology))--University of Stellenbosch, 1996.


The work presented in this thesis has contributed to the clarification of a number of issues related to the clinical pharmacokinetics of isoniazid and hydrozine in juvenile and adult patients of both sexes subject to potentially deleterious environmental factors: acute tuberculous disease; nutritional deprivation; simultaneous ingestion of rifampicin, pyrazinamide and ethionamide, each of which is potentially toxic in its own right. The advances are embodied in the developments listed here below. ...

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/1267
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