Sequence analysis of near full-length HIV type 1 subtype D primary strains isolated in Cape Town, South Africa, from 1984 to 1986
Date
2005
Authors
Loxton A.G.
Treurnicht F.
Laten A.
Van Rensburg E.J.
Engelbrecht S.
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Abstract
South Africa has one of the fastest growing HIV-1 epidemics worldwide, consisting mostly of subtype C. However, HIV-1 subtype B and subtype D viruses were isolated in the beginning of the epidemic in the early 1980s. This study describes the amplification, cloning, and near full-length genome sequencing of four HIV-1 subtype D primary strains, isolated from 1984 to 1986 in Cape Town, in what seems to have been a small restricted subtype D epidemic in the country. © Mary Ann Liebert, Inc.
Description
Keywords
article, epidemic, gene amplification, gene sequence, Human immunodeficiency virus 1, Human immunodeficiency virus 1 subtype b, Human immunodeficiency virus 1 subtype c, human immunodeficiency virus 1 subtype d, Human immunodeficiency virus infection, molecular cloning, nonhuman, nucleotide sequence, priority journal, South Africa, subspecies, virus isolation, virus strain, Disease Outbreaks, Genome, Viral, HIV Infections, HIV-1, Humans, Male, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA, South Africa
Citation
AIDS Research and Human Retroviruses
21
5
21
5