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How good are our guidelines? Four years of experience with the SAMJ’s AGREE II review of submitted clinical practice guideline

Kredo, Tamara; Wiseman, Roger; Gray, Andy; Parrish, Andy; Miot, Jacqui; Cohen, Karen; Jamaloodien, Khadija; Blockman, Marc (Health & Medical Publishing Group, 2018)

The South African Medical Journal (SAMJ) is an established source of clinical practice guidelines (CPGs) serving the local healthcare community. CPGs link professional societies and clinicians by guiding best practice ...
Deposition and transport of linezolid mediated by a synthetic surfactant Synsurf® within a pressurized metered dose inhaler : a Calu-3 model

Van Rensburg, Lyne; Van Zyl, Johann M.; Smith, Johan (Dove Medical Press, 2018)

Background: Previous studies in our laboratory demonstrated that a synthetic peptide containing lung surfactant enhances the permeability of chemical compounds through bronchial epithelium. The purpose of this study was ...
B-cell and T-cell activation in South African HIV-1-positive non-Hodgkin’s lymphoma patients

Flepisi, Brian T.; Bouic, Patrick; Sissolak, Gerhard; Rosenkranz, Bernd (Medpharm Publications, 2018)

Background: Altered immune mechanisms play a critical role in the pathogenesis of non-Hodgkin’s lymphoma (NHL). HIV-1 (HIV) infection is associated with a state of excessive T-cell activation, which can lead to increased ...