Variation in HIV prevalence and the population-level effects of antiretroviral therapy in reducing tuberculosis incidence in South Africa

Sloot, R. ; Maarman, G. J. ; Osman, M. ; Marx, F. M. (2018)

CITATION: Sloot, R. et al. 2018. Variation in HIV prevalence and the population-level effects of antiretroviral therapy in reducing tuberculosis incidence in South Africa. South African Medical Journal, 108(8):606, doi:10.7196/SAMJ.2018.v108i8.13394.

The original publication is available at http://www.samj.org.za

Article

The current year (2018) marks the 10th year after the tuberculosis (TB) epidemic in South Africa (SA) reached a historic peak of 848 incident TB cases per 100 000 population in 2008.[1,2] TB incidence has since decreased at an average of 2.0% annually to 781 per 100 000 in 2016.[1,2] The decline observed in the past decade has mainly been attributed to the expansion of HIV testing and antiretroviral therapy (ART).[1,2] Despite these and other public health efforts, TB remains a leading cause of death in SA,[1] and at the current rate of decline, SA will not reach the 2035 targets of the End TB Strategy.

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