Now showing items 11-16 of 16
Antiretroviral therapy in children - increased benefit from increased complexity
(Health & Medical Publishing Group, 2000-10)
Antiretroviral therapy (ART) started as monotherapy with significant short-term gains. With the advent of newer drugs management has become more complex, but with significant gains in quality and quantity of life. The ...
Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy
(Wiley Open Access, 2018)
Introduction: Early antiretroviral therapy (ART) has improved neurodevelopmental outcomes of HIV-infected (HIV-positive) children; however, little is known about the longer term outcomes in infants commencing early ART ...
Thymic output and CD4 T-cell reconstitution in HIV-infected children on early and interrupted antiretroviral treatment : evidence from the children with HIV early antiretroviral therapy trial
Objectives: Early treatment of HIV-infected children and adults is important for optimal immune reconstitution. Infants’ immune systems are more plastic and dynamic than older children’s or adults’, and deserve particular ...
Paediatric ART outcomes in a decentralised model of care in Cape Town, South Africa
(AOSIS Publishing, 2014-01-05)
Background. Although subSaharan Africa faces the world’s largest paediatric HIV epidemic, only 1 in 4 children has access to combination antiretroviral therapy (ART). A decentralised approach to HIV care is advocated, but ...
Current perspectives on paediatric HIV management from the Mexico International Aids Society Conference, 2019
ENGLISH ABSTRACT: While acknowledging the great achievements in getting 23 million people living with HIV to access antiretroviral treatment (ART) globally, there is still more to do in order to close the HIV treatment ...
Lamivudine monotherapy as a holding regimen for HIV-positive children
(Public Library of Science, 2018-10-11)
Background: In resource-limited settings holding regimens, such as lamivudine monotherapy (LM), are used to manage HIV-positive children failing combination antiretroviral therapy (cART) to mitigate the risk of drug ...