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Now showing items 11-20 of 321
The cost of nephroblastoma treatment in South Africa : a very cost-effective investment with guidelines for the rest of Africa
(Health & Medical Publishing Group, 2014-11-13)
Background. Nephroblastoma is one of the most common childhood malignancies in Africa, but with a survival rate significantly lower than in developed countries. In African countries with a small gross domestic product (GDP) ...
Retinoblastoma outcome at a single institution in South Africa
(Health & Medical Publishing Group, 2014-12)
Introduction. Retinoblastoma (RB) is the most common eye cancer in children. Early detection is necessary for cure.
Objective. To compare stage and outcome of children with RB treated at Kalafong Hospital, Pretoria, South ...
Tuberculous meningitis in infants and children : insights from nuclear magnetic resonance metabolomics
(Academy of Science of South Africa, 2016-03)
Tuberculous meningitis (TBM) is a prevalent form of central nervous system tuberculosis (CNS-TB) and the most severe common form of bacterial meningitis in infants and children below the age of 13 years, especially in the ...
Children with disabling chronic conditions in the Western health subdistrict of Cape Town, South Africa : estimating numbers and service gaps
(Health & Medical Publishing Group, 2016-02-22)
Background. Children with disabling chronic conditions often have extensive, complex and unmet healthcare and educational needs. They can be defined as a subset of the group of children with chronic health conditions whose ...
Early ART results in greater immune reconstitution benefits in HIV-infected infants : working with data missingness in a longitudinal dataset
(Public Library of Science, 2015)
Background:
Early initiation of anti-retroviral treatment (ART) decreases mortality as compared to deferred treatment, but whether it preserves immune cells from early loss or promotes their recovery remains undefined. ...
Optimizing mycobacterial culture in smear- negative, human immunodeficiency virus- infected tuberculosis cases
(Public Library of Science, 2015)
Introduction:
Tuberculosis (TB) is a significant public health problem and the diagnosis in human immunodeficiency virus (HIV)—infected individuals is challenging. The use of mycobacterial culture remains an important ...
Comparing tuberculosis diagnostic yield in smear/culture and xpert MTB/RIF-based algorithms using a non-randomised stepped-wedge design
(Public Library of Science, 2016-03)
Setting Primary health services in Cape Town, South Africa. Study Aim To compare tuberculosis (TB) diagnostic yield in an existing smear/culture-based and a newly introduced Xpert MTB/RIF-based algorithm. Methods TB ...
Larger subcortical gray matter structures and smaller corpora callosa at age 5 years in HIV infected children on early ART
(Frontiers Media, 2017)
Sub-Saharan Africa is home to 90% of HIV infected (HIV+) children. Since the advent of antiretroviral therapy (ART), HIV/AIDS has transitioned to a chronic condition where central nervous system (CNS) damage may be ongoing. ...
Why healthcare workers are sick of TB
(Elsevier, 2015)
Dr Thato Mosidi never expected to be diagnosed with tuberculosis (TB), despite widely prevalent exposure and very limited infection control measures. The life-threatening diagnosis of primary extensively drug-resistant TB ...
The PREVENT study to evaluate the effectiveness and acceptability of a community-based intervention to prevent childhood tuberculosis in Lesotho : study protocol for a cluster randomized controlled trial
(BioMed Central, 2017-11-21)
Background:
Effective, evidence-based interventions to prevent childhood tuberculosis (TB) in high TB/HIV-burden, resource-limited settings are urgently needed. There is limited implementation of evidence-based contact ...