Two Cape Colored siblings with typical features of Hurler's syndrome, but without mucopolysacchariduria or mucopolysaccharide accumulation in tissues, are presented. The clinical features, in conjunction with raised β D ...

Due to the fixed karotype and documented malignancy risk in patients with Down's syndrome, recently described aetiological factors can be assigned to their proper places in a conceptual framework for leukaemogenesis in ...

Electron microscopic and hematologic investigation of peripheral blood showed a higher percentage of leukemia like nuclear ultrastructural abnormalities in the leucocytes of 30 individuals with Down's syndrome (mean 6,3%) ...

4 Patients with bacterial meningitis are reported. On initial examination, 1 patient had a slightly abnormal cerebrospinal fluid (CSF), and in the other 3 patients, the CSF was completely normal. An obviously purulent CSF ...

[No abstract available]

Two siblings had suffered from cyanosis since birth owing to the presence of Hb M(Iwate). The diagnosis was confirmed by electrophoresis, spectroscopy and peptide analysis. The benign nature of this unusual condition is stressed.

Splenic torsion as a complication of wandering spleen is rare. The authors report the clinical findings, diagnostic problems and treatment of a 1-year-old Coloured child (with classic 'prune belly syndrome') in whom the ...