Now showing items 11-20 of 25
Drug-resistant tuberculosis and advances in the treatment of childhood tuberculosis
(BioMed Central, 2016-11-24)
Over the last 10 years, interest in pediatric tuberculosis (TB) has increased dramatically, together with increased funding and research. We have a better understanding of the burden of childhood TB as well as a better ...
Assessing the impact of multidrug-resistant tuberculosis in children : an exploratory qualitative study
(BioMed Central, 2014-08)
Background: While the prevalence of multidrug-resistant (MDR) tuberculosis (TB) is high among children in the Western Cape of South Africa, the psychosocial implications of treatment for children with MDR-TB remain ...
BCG vaccination in South African HIV-exposed infants : risks and benefits
(Health and Medical Publishing Group (HMPG), 2009-02)
Adherence to isoniazid preventive chemotherapy: a prospective community based study
(BMJ Publishing Group, 2006-09)
Background: Current international guidelines recommend 6–9 months of isoniazid (INH) preventive chemotherapy to prevent the development of active tuberculosis in children exposed to a susceptible strain of M tuberculosis. ...
Infective endocarditis - The effect of liposomes as carrier substance for α1-antitrypsin and amicillin
(Health & Medical Publishing Group, 1991)
Infective endocarditis has a high mortality and morbidity rate despite all available treatment. Little attention has been paid to the possible role of polymorphonuclear leucocytes in damage to the heart valves. It was ...
Missed opportunities in the diagnosis of pulmonary tuberculosis in children
(Health & Medical Publishing Group, 1993)
In 52% of children with confirmed and probable tuberculosis the diagnosis could have been made earlier than it was. The main clinical clues which should have led to suspicion of tuberculosis were close adult contacts and ...
Risk factors for infection and disease in child contacts of multidrug-resistant tuberculosis : a cross-sectional study
(BioMed Central, 2013-08)
Background: Young children exposed to Mycobacterium tuberculosis have a high risk of disease progression following infection. This study aimed to determine risk factors for M. tuberculosis infection and disease in children ...
Rifampicin resistance in Mycobacterium tuberculosis : rapid detection and implications in chemotherapy
(Health & Medical Publishing Group, 1996-01)
Objectives. Tuberculosis treatment and susceptibility testing are cumbersome, especially in the case of multidrug-resistant (MDR) Mycobacterium tuberculosis. It is known that mutations in the rpoB gene of M. tuberculosis ...
Novel application of NIH case definitions in a paediatric tuberculosis contact investigation study
(International Union Against Tuberculosis and Lung Disease, 2015-04)
BACKGROUND: International (National Institutes of Health [NIH]) case definitions have been proposed for paediatric tuberculosis (TB) diagnostic studies. The relevance of these definitions for contact tracing studies is ...
The prevalence of symptoms associated with pulmonary tuberculosis in randomly selected children from a high burden community
(BMJ Publishing Group, 2005-11)
Background: Diagnosis of childhood tuberculosis is problematic and symptom based diagnostic approaches are often promoted in high burden settings. This study aimed (i) to document the prevalence of symptoms associated ...