Now showing items 1-10 of 13
Why healthcare workers are sick of TB
Dr Thato Mosidi never expected to be diagnosed with tuberculosis (TB), despite widely prevalent exposure and very limited infection control measures. The life-threatening diagnosis of primary extensively drug-resistant TB ...
The association of hyperglycaemia with prevalent tuberculosis : a population-based cross-sectional study
(BioMed Central, 2016)
Background: Systematic reviews suggest that the incidence of diagnosed tuberculosis is two- to- three times higher in those with diabetes mellitus than in those without. Few studies have previously reported the ...
The treatment of tuberculosis in childhood
Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens
(Public Library of Science (PLOS), 2008-08)
Global tuberculosis control is threatened by dramatic increases in HIV-related tuberculosis and by the emergence of multidrug-resistant strains. Highly lethal outbreaks of extensively drugresistant tuberculosis among ...
Tuberculosis and pneumonia in HIV-infected children : an overview
(BioMed Central, 2016-11-24)
ENGLISH ABSTRACT: Pneumonia remains the most common cause of hospitalization and the most important cause of death in young children. In high human immunodeficiency virus (HIV)-burden settings, HIV-infected children carry ...
The recombinant bacille Calmette–Guerin vaccine VPM1002 : ready for clinical efficacy testing
The only licensed vaccine against tuberculosis (TB), bacille Calmette–Guérin (BCG), protects against severe extrapulmonary forms of TB but is virtually ineffective against the most prevalent form of the disease, pulmonary ...
Variation in HIV prevalence and the population-level effects of antiretroviral therapy in reducing tuberculosis incidence in South Africa
(Health & Medical Publishing Group, 2018)
The current year (2018) marks the 10th year after the tuberculosis (TB) epidemic in South Africa (SA) reached a historic peak of 848 incident TB cases per 100 000 population in 2008.[1,2] TB incidence has since decreased ...
Treatment and outcomes in children with multidrug-resistant tuberculosis : a systematic review and individual patient data meta-analysis.
(Public Library of Science, 2018-07-11)
Background: An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-TB; Mycobacterium tuberculosis resistant to isoniazid and rifampin) each year. Little is known about the optimal treatment for these ...
Potential of host serum protein biomarkers in the diagnosis of tuberculous meningitis in children
(Frontiers Media, 2019)
Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis and results in high morbidity and mortality in children. Diagnostic delay contributes to the poor outcome. There is an urgent need for new ...
BCG vaccination in South African HIV-exposed infants : risks and benefits
(Health and Medical Publishing Group (HMPG), 2009-02)