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Variation in HIV prevalence and the population-level effects of antiretroviral therapy in reducing tuberculosis incidence in South Africa
(Health & Medical Publishing Group, 2018)
The current year (2018) marks the 10th year after the tuberculosis (TB) epidemic in South Africa (SA) reached a historic peak of 848 incident TB cases per 100 000 population in 2008.[1,2] TB incidence has since decreased ...
Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy
(Wiley Open Access, 2018)
Introduction: Early antiretroviral therapy (ART) has improved neurodevelopmental outcomes of HIV-infected (HIV-positive)
children; however, little is known about the longer term outcomes in infants commencing early ART ...
Lamivudine monotherapy as a holding regimen for HIV-positive children
(Public Library of Science, 2018-10-11)
Background:
In resource-limited settings holding regimens, such as lamivudine monotherapy (LM), are used to manage HIV-positive children failing combination antiretroviral therapy (cART) to mitigate the risk of drug ...