Now showing items 1-4 of 4
Larger subcortical gray matter structures and smaller corpora callosa at age 5 years in HIV infected children on early ART
(Frontiers Media, 2017)
Sub-Saharan Africa is home to 90% of HIV infected (HIV+) children. Since the advent of antiretroviral therapy (ART), HIV/AIDS has transitioned to a chronic condition where central nervous system (CNS) damage may be ongoing. ...
No evidence of HIV replication in children on antiretroviral therapy
(American Society for Clinical Investigation, 2017-04)
ENGLISH ABSTRACT: It remains controversial whether current antiretroviral therapy (ART) fully suppresses the cycles of HIV replication and viral evolution in vivo. If replication persists in sanctuary sites such as the ...
A universal testing and treatment intervention to improve HIV control : one-year results from intervention communities in Zambia in the HPTN 071 (PopART) cluster-randomised trial
(Public Library of Science, 2017)
Background: The Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 targets require that, by 2020, 90% of those living with HIV know their status, 90% of known HIV-positive individuals receive sustained antiretroviral ...
Thymic output and CD4 T-cell reconstitution in HIV-infected children on early and interrupted antiretroviral treatment : evidence from the children with HIV early antiretroviral therapy trial
Objectives: Early treatment of HIV-infected children and adults is important for optimal immune reconstitution. Infants’ immune systems are more plastic and dynamic than older children’s or adults’, and deserve particular ...