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Now showing items 1-10 of 16
It is time to consider third-line options in antiretroviral-experienced paediatric patients?
(BioMed Central, 2011-11)
Abstract Background The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of ...
Trends in paediatric bloodstream infections at a South African referral hospital
(BioMed Central, 2015-04)
Background: The epidemiology of paediatric bloodstream infection (BSI) in Sub-Saharan Africa is poorly documented
with limited data on hospital-acquired sepsis, impact of HIV infection, BSI trends and antimicrobial ...
Universal children’s day : let’s improve current interventions to reduce vertical transmission of HIV now
(International AIDS society, 2014-11-20)
By 2013, there was a 40% decline in new paediatric infections compared to 2009. Prevention of mother to child transmission (PMTCT) of HIV continues to reduce the frequency of HIV in infants through wider and earlier ...
When to start antiretroviral therapy in infants and children
(AOSIS OpenJournals, 2009-12)
This articles provides a background for antiretroviral therapy in infants and children, incorporating both old and new data. There is increasing data favouring early therapy for all age groups. Below a year of age, all ...
High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy : a cross-sectional study
(BioMed Central, 2012-11)
Background: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching ...
Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007 : the IeDEA Southern Africa collaboration
(Health and Medical Publishing Group (HMPG), 2009-09)
Objectives. To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South African national antiretroviral ...
Outcomes of the South African national antiretroviral treatment programme for children : the IeDEA southern Africa collaboration
(Health and Medical Publishing Group (HMPG), 2009-10)
Objectives. To assess paediatric antiretroviral treatment (ART) outcomes and their associations from a collaborative cohort representing 20% of the South African national treatment programme. Design and setting. Multi-cohort ...
Early antiretroviral therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy : evidence from the Children with HIV Early antiretroviral therapy (CHER) Study.
(2011-10)
Abstract Background Although otorrhea occurs commonly in HIV-infected infants, there are few data. We compared the incidence of otorrhea in infants receiving early vs deferred ART in the Children with HIV Early Antiretroviral ...
Tuberculosis and pneumonia in HIV-infected children : an overview
(BioMed Central, 2016-11-24)
ENGLISH ABSTRACT: Pneumonia remains the most common cause of hospitalization and the most important cause of death in young children. In high human immunodeficiency virus (HIV)-burden settings, HIV-infected children carry ...
When to start antiretroviral therapy in children aged 2-5 years : a collaborative causal modelling analysis of cohort studies from Southern Africa
(PLoS, 2013-11-19)
Background
There is limited evidence on the optimal timing of antiretroviral therapy (ART) initiation in children 2–5 y of age. We conducted a causal modelling analysis using the International Epidemiologic Databases ...