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Missing HIV prevention opportunities in South African children – A 7-year review

Feucht, Ute D.; Meyer, Anell; Kruger, Mariana (BioMed Central, 2014-12-13)

Background: The prevention of mother-to-child transmission (PMTCT) program in South Africa is now successful in ensuring HIV-free survival for most HIV-exposed children, but gaps in PMTCT coverage remain. The study ...

Treatment of young children with HIV infection : using evidence to inform policymakers

Prendergast, A. J.; Penazzato, M.; Cotton, M. F.; Musoke, P.; Mulenga, V.; Abrams, E. J.; Gibb, D. M. (Public Library of Science, 2012-07-24)

No abstract available.

Missed opportunities of inclusion in a cohort of HIV-infected children to initiate antiretroviral treatment before the age of two in West Africa, 2011 to 2013

Dahourou, Desire L.; Amorissani-Folquet, Madeleine; Coulibaly, Malik; Avit-Edi, Divine; Meda, Nicolas; Timite-Konan, Marguerite; Arendt, Vic; Ye, Diarra; Amani-Bosse, Clarisse; Salamon, Roger; Lepage, Philippe; Leroy, Valeriane; Cotton, Mark (International AIDS Society, 2016-03-23)

Introduction: The World Health Organization (WHO) 2010 guidelines recommended to treat all HIV-infected children less than two years of age. We described the inclusion process and its correlates of HIV-infected children ...

When to start antiretroviral therapy in children aged 2-5 years : a collaborative causal modelling analysis of cohort studies from Southern Africa

Schomaker, Michael; Egger, Matthias; Ndirangu, James; Moultrie, Harri; Technau, Karl; Cox, Vivian; Giddy, Janet; Phiri, Sam; Chimbetete, Cleophas; Wood, Robin; Gsponer, Thomas; Moore, Carolyn Bolton; Rabie, Helena; Eley, Brian; Muhe, Lulu; Penazzato, Martina; Essajee, Shaffiq; Keiser, Olivia; Davies, Mary-Ann (PLoS, 2013-11-19)

Background There is limited evidence on the optimal timing of antiretroviral therapy (ART) initiation in children 2–5 y of age. We conducted a causal modelling analysis using the International Epidemiologic Databases ...

Thymic output and CD4 T-cell reconstitution in HIV-infected children on early and interrupted antiretroviral treatment : evidence from the children with HIV early antiretroviral therapy trial

Lewis, Joanna; Payne, Helen; Walker, A. Sarah; Otwombe, Kennedy; Gibb, Diana M.; Babiker, Abdel G.; Panchia, Ravindre; Cotton, Mark F.; Violari, Avy; Klein, Nigel; Callard, Robin E. (Frontiers, 2017-09)

Objectives: Early treatment of HIV-infected children and adults is important for optimal immune reconstitution. Infants’ immune systems are more plastic and dynamic than older children’s or adults’, and deserve particular ...

Kaposi’s sarcoma : good outcome with doxorubicin, bleomycin and vincristine sulphate (ABV) chemotherapy and highly active antiretroviral therapy

Hesseling, P. B.; Katayi, E.; Wharin, P.; Bardin, R.; Kouya, F.; Palmer, D.; Glenn, M.; Kruger, Mariana (Health & Medical Publishing Group, 2017)

There is little published information on effective treatment of Kaposi’s sarcoma (KS) in children in low-income countries. We prospectively treated 12 patients with an institutional review board-approved protocol consisting ...