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Impact of pulsed xenon ultraviolet disinfection on surface contamination in a hospital facility’s expressed human milk feed preparation area
(BioMed Central, 2018-02-23)
Background;
Expressed human milk (EHM) feed preparation areas represent a potential source of unintentional nosocomial infection. Daily disinfection of environmental surfaces remains an essential intervention to mitigate ...
Factors influencing access of pregnant women and their infants to their local healthcare system : a prospective, multi-centre, observational study
(BioMed Central, 2018-01-15)
Background:
The successful implementation of maternal vaccination relies on results of clinical trials, considering the prenatal and postnatal attendance at selected healthcare institutions. This study evaluated factors ...
The contribution of a community based HIV Counseling and Testing (HCT) initiative in working towards increasing access to HIV counseling and testing in Cape Town, South Africa
(Stellenbosch : Stellenbosch University, 2018-03)
ENGLISH ABSTRACT: HIV testing services (HTS) play an important role in South Africa’s response to the HIV epidemic
and within the UNAIDS ‘90-90-90’ strategy. Reaching the first ‘90’, diagnosing 90% of
individuals unaware ...
The wonder years : what can primary school children teach us about immunity to mycobacterium tuberculosis?
(Frontiers Media, 2018)
ENGLISH ABSTRACT: In high burden settings, the risk of infection with Mycobacterium tuberculosis increases throughout childhood due to cumulative exposure. However, the risk of progressing from tuberculosis (TB) infection ...
Human monocytic suppressive cells promote replication of mycobacterium tuberculosis and alter stability of in vitro generated granulomas
(Frontiers Media, 2018)
ENGLISH ABSTRACT: Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is characterized by the development of unique tissue lesions, termed granulomas. These lesions encompass ...
A retrospective review of Listeria monocytogenes infection at Tygerberg Children’s Hospital, Cape Town, South Africa, from 2006 to 2016 : is empirical ampicillin still indicated after the first month of life?
(Health & Medical Publishing Group, 2018)
Background. Ampicillin to treat Listeria monocytogenes (LM) infection is empirically added to the treatment of infants (<3 months) with suspected sepsis or meningitis.
Objectives. In view of limited LM cases, the paucity ...
Ethical considerations in the application of cell and gene therapies in children
(Health & Medical Publishing Group, 2018)
ENGLISH ABSTRACT: Rapidly evolving fields such as cell and gene therapies that involve state-of-the-art technology hold out possibilities that may be ahead of what ethics, guidelines and the law have considered. This results ...
The diagnosis of asthma in children : an evidence-based approach to a common clinical dilemma
(Medical Publishing Group, 2018)
Background. Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, as well as airway reversibility. The diagnosis of asthma in young children is limited by the ...
Variation in HIV prevalence and the population-level effects of antiretroviral therapy in reducing tuberculosis incidence in South Africa
(Health & Medical Publishing Group, 2018)
The current year (2018) marks the 10th year after the tuberculosis (TB) epidemic in South Africa (SA) reached a historic peak of 848 incident TB cases per 100 000 population in 2008.[1,2] TB incidence has since decreased ...
Treatment and outcomes in children with multidrug-resistant tuberculosis : a systematic review and individual patient data meta-analysis.
(Public Library of Science, 2018-07-11)
Background:
An estimated 32,000 children develop multidrug-resistant tuberculosis (MDR-TB; Mycobacterium
tuberculosis resistant to isoniazid and rifampin) each year. Little is known about the
optimal treatment for these ...