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Now showing items 1-10 of 13
It is time to consider third-line options in antiretroviral-experienced paediatric patients?
(BioMed Central, 2011-11)
Abstract Background The historic use of full-dose ritonavir as part of an unboosted protease inhibitor (PI)-based antiretroviral therapy regimen in some South African children contributes to the frequent accumulation of ...
Trends in paediatric bloodstream infections at a South African referral hospital
(BioMed Central, 2015-04)
Background: The epidemiology of paediatric bloodstream infection (BSI) in Sub-Saharan Africa is poorly documented
with limited data on hospital-acquired sepsis, impact of HIV infection, BSI trends and antimicrobial ...
Universal children’s day : let’s improve current interventions to reduce vertical transmission of HIV now
(International AIDS society, 2014-11-20)
By 2013, there was a 40% decline in new paediatric infections compared to 2009. Prevention of mother to child transmission (PMTCT) of HIV continues to reduce the frequency of HIV in infants through wider and earlier ...
High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy : a cross-sectional study
(BioMed Central, 2012-11)
Background: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching ...
Early antiretroviral therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy : evidence from the Children with HIV Early antiretroviral therapy (CHER) Study.
(2011-10)
Abstract Background Although otorrhea occurs commonly in HIV-infected infants, there are few data. We compared the incidence of otorrhea in infants receiving early vs deferred ART in the Children with HIV Early Antiretroviral ...
Tuberculosis and pneumonia in HIV-infected children : an overview
(BioMed Central, 2016-11-24)
ENGLISH ABSTRACT: Pneumonia remains the most common cause of hospitalization and the most important cause of death in young children. In high human immunodeficiency virus (HIV)-burden settings, HIV-infected children carry ...
When to start antiretroviral therapy in children aged 2-5 years : a collaborative causal modelling analysis of cohort studies from Southern Africa
(PLoS, 2013-11-19)
Background
There is limited evidence on the optimal timing of antiretroviral therapy (ART) initiation in children 2–5 y of age. We conducted a causal modelling analysis using the International Epidemiologic Databases ...
Tuberculosis : opportunities and challenges for the 90-90-90 targets in HIV-infected children
(International AIDS Society, 2015-12-02)
Introduction: In 2014 the Joint United Nations Programme on HIV/AIDS defined the ambitious 90 90 90 targets for 2020, in
which 90% of people living with HIV must be diagnosed, 90% of those diagnosed should be on sustained ...
The last and first frontier : emerging challenges for HIV treatment and prevention in the first week of life with emphasis on premature and low birth weight infants
(International AIDS Society, 2015-12-02)
Abstract
Introduction: There is new emphasis on identifying and treating HIV in the first days of life and also an appreciation that low
birth weight (LBW) and preterm delivery (PTD) frequently accompany HIV-related ...
Where do HIV-infected adolescents go after transfer? – Tracking transition/transfer of HIV-infected adolescents using linkage of cohort data to a health information system platform
(Wiley Open Access, 2017)
Introduction: To evaluate long-term outcomes in HIV-infected adolescents, it is important to identify ways of tracking
outcomes after transfer to a different health facility. The Department of Health (DoH) in the Western ...