Now showing items 1-3 of 3
High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy : a cross-sectional study
(BioMed Central, 2012-11)
Background: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching ...
Ontogeny of toll-like receptor mediated cytokine responses of South African infants throughout the first year of life
(Public Library of Science, 2012-09-13)
The first year of life represents a time of marked susceptibility to infections; this is particularly true for regions in sub-Saharan Africa. As innate immunity directs the adaptive immune response, the observed increased ...
Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children
(Massachusetts Medical Society, 2012)
BACKGROUND: Nevirapine-based antiretroviral therapy is the predominant (and often the only) regimen available for children in resource-limited settings. Nevirapine resistance after exposure to the drug for prevention of ...