• Early severe HIV disease precedes early antiretroviral therapy in infants : are we too late? 

      Innes, Steve; Lazarus, Erica; Otwombe, Kennedy; Afaaf Liberty, Afaaf; Germanus, Ramona; Janse Van Rensburg, Anita; Grobbelaar, Nelis; Hurter, Theunis; Eley, Brian; Violari, Avy; Cotton, Mark F. (International AIDS Society, 2014-06)
      Objective: To describe the degree of HIV disease progression in infants initiating antiretroviral therapy (ART) by three months of age in a programmatic setting in South Africa. Design: This was a programmatic cohort ...
    • High prevalence of lipoatrophy in pre-pubertal South African children on antiretroviral therapy : a cross-sectional study 

      Innes, Steve; Cotton, Mark F.; Haubrich, Richard; Conradie, Maria M.; Van Niekerk, Margaret; Edson, Clair; Rabie, Helena; Jain, Sonia; Sun, Xiaoying; Zollner, Ekkehard W.; Hough, Stephen; Browne, Sara H. (BioMed Central, 2012-11)
      Background: Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reaching ...
    • Low-dose stavudine trials: a public health priority for developing countries 

      Venter, W. D. Francois; Innes, Steve; Cotton, Mark (AOSIS Publishing, 2012-03-13)
      The debate around relooking at stavudine dosing, both in terms of the adult low-dose stavudine study and more broadly, is welcome. The study being proposed to evaluate low-dose stavudine v. tenofovir is a fairly standard ...