ITEM VIEW

The impact of HIV infection on the presentation of lung cancer in South Africa

dc.contributor.authorKoegelenberg, C. F. N.en_ZA
dc.contributor.authorVan Der Made, T.en_ZA
dc.contributor.authorTaljaard, J. J.en_ZA
dc.contributor.authorIrusen, E. M.en_ZA
dc.date.accessioned2017-10-16T08:32:31Z
dc.date.available2017-10-16T08:32:31Z
dc.date.issued2016
dc.identifier.citationKoegelenberg, C. F. N., et al. 2016. The impact of HIV infection on the presentation of lung cancer in South Africa. South African Medical Journal, 106(7):666-668, doi:10.7196/SAMJ.2016.v106i7.10737
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.otherdoi:10.7196/SAMJ.2016.v106i7.10737
dc.identifier.urihttp://hdl.handle.net/10019.1/102333
dc.descriptionCITATION: Koegelenberg, C. F. N., et al. 2016. The impact of HIV infection on the presentation of lung cancer in South Africa. South African Medical Journal, 106(7):666-668, doi:10.7196/SAMJ.2016.v106i7.10737.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractENGLISH ABSTRACT: Background. Despite the very high background prevalence of HIV and smoking-related diseases in sub-Saharan Africa, very little is known about the presentation of lung cancer in HIV-infected individuals. Methods. We prospectively compared HIV-positive (n=44) and HIV-negative lung cancer patients (n=425) with regard to demographics, cell type, performance status and umour node metastasis staging at initial presentation. Results. HIV-positive patients were found to be younger than HIV-negative (mean 54.1 (standard deviation (SD) 8.4) years v. 60.5 (10) years, p<0.01), more likely to have squamous cell carcinoma (43.2% v. 30.1%, p=0.07) and significantly more likely to have a poor Eastern Cooperative Oncology Group (ECOG) performance status of ≥3 (47.7% v. 29.4%, p=0.02). In the case of non-small cell-lung cancer, they were also significantly less likely to have early stage lung cancer (0% v. 10.3%, p=0.02) compared with HIV-negative patients. Conclusions. HIV-positive lung cancer patients were younger, significantly more likely to have a poor performance status at presentation and significantly less likely to have early stage lung cancer when compared with HIV-negative patients.en_ZA
dc.description.abstractAFRIKAANSE OPSOMMING: Geen opsomming beskikbaaraf_ZA
dc.description.urihttp://www.samj.org.za/index.php/samj/article/view/10737
dc.format.extent3 pagesen_ZA
dc.language.isoen_ZAen_ZA
dc.publisherHealth & Medical Publishing Group
dc.subjectHIV-positive personsen_ZA
dc.subjectLung canceren_ZA
dc.subjectBronchoscopyen_ZA
dc.titleThe impact of HIV infection on the presentation of lung cancer in South Africaen_ZA
dc.typeArticleen_ZA
dc.description.versionPublisher's version
dc.rights.holderSouth African Medical Journal


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

ITEM VIEW