A descriptive study to determine the prevalence of TPMT polymorphism in Healthy male subjects in Central South Africa

Date
2014-03
Journal Title
Journal ISSN
Volume Title
Publisher
Stellenbosch : Stellenbosch University
Abstract
ENGLISH SUMMARY : Thiopurine medications e.g. Azathioprine and 6-Mercaptopurine are metabolized by the thiopurine methyltransferase (TPMT) enzyme. This enzyme activity is highly variable due to polymorphism of the TPMT gene. TPMT genotyping can be performed to tailor the treatment with thiopurine medications specifically to the patient's TPMT activity.
AFRIKAANSE OPSOMMING : Geen opsomming beskikbaar.
Description
Thesis (MMed)--Stellenbosch University, 2014.
Keywords
Chromosome polymorphism -- Male patients -- South Africa, Chromosome polymorphism -- Incidence -- South Africa, UCTD
Citation