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The effects of longitudinal HIV viral load exposure on immune outcomes, mortality, and opportunistic infections in people on ART in sub-Saharan Africa
(Stellenbosch : Stellenbosch University, 2017-12)
ENGLISH SUMMARY : Introduction: Longitudinal viral load monitoring is used as a cross-sectional marker for
treatment failure in HIV infected people receiving antiretroviral therapy. Cumulative viral load, as quantified ...
Evaluation of the Mean Duration of Recent Infection (MDRI) and the False Recent Rate (FRR) for the Limiting Antigen Avidity Enzyme Immune Assay (LAg) and Bio-Rad HIV ½ Plus O Avidity Incidence Assay (BRAI)
(Stellenbosch : Stellenbosch University, 2017-12)
ENGLISH SUMMARY : Background: The evaluation of laboratory assays in estimating HIV incidence has become a priority because of the complexity of HIV epidemics and the need to measure the impact of public health interventions ...
Completeness of HIV intervention trial protocols : a systematic survey
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Introduction: The Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT1) 2013 guideline provides guidance to improve the quality of protocols. The aim of this study was to determine ...
Barriers and facilitators to linkage, adherence and retention in care among HIV positive patients : an overview of qualitative systematic reviews using mega-aggregation framework synthesis
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Background: People living with Human Immunodeficiency Virus (PLHIV) continue to struggle with the complexities related to having a chronic disease and integrating antiretroviral treatment (ART) and care ...
Understanding the relationship between vaccination, vaccine-preventable diseases, and HIV infection among sub-Saharan African children
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Numerous care and treatment guidelines pinpoint vaccination as a crucial preventive strategy for HIV-infected patients, but data regarding these vaccines among children living with HIV are still very ...
Mechanical debridement with antibiotics in the treatment of chronic periodontitis : effect on systemic biomarkers : a systematic review
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Background: Chronic periodontitis is an inflammatory oral disease which leads to the destruction of the supporting tissues of the teeth, leading to bone resorption and tooth loss. Destruction of the ...
Transcutaneous bilirubin screening for hyperbilirubinemia in African newborns
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Background: In many parts of the world, including African countries, apparently healthy newborns are usually discharged home early. Serum bilirubin levels usually peaks on postnatal days 3 to 5, by when ...
Prevalence of non-communicable diseases in adults living with Human Immunodeficiency Virus : an overview of systematic reviews
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Background: Non-communicable diseases (NCD’s) are on the rise in patients with HIV and this has been partly attributed to the increasing use of Antiretroviral therapy (ART). Our aim was to consolidate ...
The use of error reporting data in patient safety research
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Background: Error reporting is the only data source designed specifically to generate patient safety data, yet its ability to report comprehensively on patient safety has not been assessed. This study ...