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Predictors of mortality in adults on treatment for human immunodeficiency virus-associated tuberculosis in Botswana : a retrospective cohort study
(Wolters Kluwer Health, 2018)
Mortality in patients with human immunodeficiency virus (HIV)-associated tuberculosis (TB) is high, particularly in sub-Saharan Africa.
This study aimed to compare mortality and predictors of mortality in those who were ...
HIV infection and the epidemiology of Invasive Pneumococcal Disease (IPD) in South African adults and older children prior to the introduction of a Pneumococcal Conjugate Vaccine (PCV)
(Public Library of Science, 2016)
Introduction:
Streptococcus pneumoniae is the commonest cause of bacteremic pneumonia among HIV-infected persons. As more countries with high HIV prevalence are implementing infant pneumococcal conjugate vaccine (PCV) ...
The effects of longitudinal HIV viral load exposure on immune outcomes, mortality, and opportunistic infections in people on ART in sub-Saharan Africa
(Stellenbosch : Stellenbosch University, 2017-12)
ENGLISH SUMMARY : Introduction: Longitudinal viral load monitoring is used as a cross-sectional marker for
treatment failure in HIV infected people receiving antiretroviral therapy. Cumulative viral load, as quantified ...
A cross sectional survey to evaluate knowledge, attitudes and practices regarding seasonal influenza and influenza vaccination among diabetics in Pretoria, South Africa
(Elsevier, 2017-11-07)
Background: In South Africa, influenza vaccination is recommended to all diabetics. However, vaccinationcoverage among diabetics remains low. Therefore, this study aimed to explore the knowledge, attitudes,and practices ...
Developing prehospital clinical practice guidelines for resource limited settings : why re-invent the wheel?
(BioMed Central, 2018-02-05)
Objectives: Methods on developing new (de novo) clinical practice guidelines (CPGs) have received substantial attention. However, the volume of literature is not matched by research into alternative methods of CPG development ...
A comparative evaluation of PDQ-Evidence
(BioMed Central, 2018-03-15)
Background: A strategy for minimising the time and obstacles to accessing systematic reviews of health system
evidence is to collect them in a freely available database and make them easy to find through a simple ...
Quality of life and physical activity among older adults living in institutions compared to the community
(AOSIS Publishing, 2017)
Background: The environment of older adults plays an important role in their well-being. It influences their quality of life and physical activity level. In South Africa, there is a dearth of literature concerning this ...
Completeness of HIV intervention trial protocols : a systematic survey
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Introduction: The Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT1) 2013 guideline provides guidance to improve the quality of protocols. The aim of this study was to determine ...
Barriers and facilitators to linkage, adherence and retention in care among HIV positive patients : an overview of qualitative systematic reviews using mega-aggregation framework synthesis
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Background: People living with Human Immunodeficiency Virus (PLHIV) continue to struggle with the complexities related to having a chronic disease and integrating antiretroviral treatment (ART) and care ...
Understanding the relationship between vaccination, vaccine-preventable diseases, and HIV infection among sub-Saharan African children
(Stellenbosch : Stellenbosch University, 2019-04)
ENGLISH SUMMARY : Numerous care and treatment guidelines pinpoint vaccination as a crucial preventive strategy for HIV-infected patients, but data regarding these vaccines among children living with HIV are still very ...