Smoking and alcohol use during pregnancy affects preterm infants' docosahexaenoic acid (DHA) status

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dc.contributor.authorSmuts C.M.
dc.contributor.authorTichelaar H.Y.
dc.contributor.authorDhansay M.A.
dc.contributor.authorFaber M.
dc.contributor.authorSmith J.
dc.contributor.authorKirsten G.F.
dc.date.accessioned2011-05-15T16:15:13Z
dc.date.available2011-05-15T16:15:13Z
dc.date.issued1999
dc.description.abstractThis study investigated the effect of alcohol consumption and smoking during pregnancy on the fatty acid composition of the infants. A total of 40 very-low-birth-weight (VLBW) infants, weighing between 750 and 1500g, were enrolled in the study after being hospitalized and ventilated for respiratory distress syndrome (RDS). Maternal and infant demographic information was recorded. Questions regarding maternal smoking (none, <10 and ≥10 cigarettes/d) and alcohol consumption (none, occasionally, moderate and severe) were recorded. Erythrocyte membrane (EMB; n = 40) total fatty acid analyses were performed at birth (baseline) and on days 14 and 28 postnatally. During pregnancy, 42% of mothers consumed alcohol and 50% smoked. At birth, infants of mothers who smoked and consumed alcohol during pregnancy, had significantly higher blood docosahexaenoic acid (DHA; p < 0.05) than infants of mothers who abstained from both alcohol and smoking. The consequences of this finding remain unknown.
dc.description.versionArticle
dc.identifier.citationActa Paediatrica, International Journal of Paediatrics
dc.identifier.citation88
dc.identifier.citation7
dc.identifier.issn08035253
dc.identifier.other10.1080/08035259950169053
dc.identifier.urihttp://hdl.handle.net/10019.1/13246
dc.subjectdocosahexaenoic acid
dc.subjectalcohol consumption
dc.subjectarticle
dc.subjectcigarette smoking
dc.subjectclinical article
dc.subjecterythrocyte membrane
dc.subjectfatty acid blood level
dc.subjectfetus development
dc.subjecthuman
dc.subjectlipid composition
dc.subjectneonatal respiratory distress syndrome
dc.subjectnewborn
dc.subjectpregnancy
dc.subjectprematurity
dc.subjectprenatal exposure
dc.subjectpriority journal
dc.subjectvery low birth weight
dc.subjectAlcohol Drinking
dc.subjectDocosahexaenoic Acids
dc.subjectFemale
dc.subjectGestational Age
dc.subjectHospitalization
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectInfant, Very Low Birth Weight
dc.subjectMaternal Behavior
dc.subjectPlants, Toxic
dc.subjectPregnancy
dc.subjectPrenatal Exposure Delayed Effects
dc.subjectProspective Studies
dc.subjectRespiratory Distress Syndrome, Newborn
dc.subjectSmoking
dc.subjectTobacco
dc.titleSmoking and alcohol use during pregnancy affects preterm infants' docosahexaenoic acid (DHA) status
dc.typeArticle
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