Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens

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dc.contributor.authorBurman, William J.
dc.contributor.authorCotton, Mark F.
dc.contributor.authorGibb, Diana M.
dc.contributor.authorWalker, A. Sarah
dc.contributor.authorVernon, Andrew A.
dc.contributor.authorDonald, Peter R.
dc.date.accessioned2012-07-30T13:25:44Z
dc.date.available2012-07-30T13:25:44Z
dc.date.issued2008-08
dc.descriptionThe Essay Sectionen_ZA
dc.descriptionThe original publication is available at http://www.plosmedicine.orgen_ZA
dc.description.abstractGlobal tuberculosis control is threatened by dramatic increases in HIV-related tuberculosis and by the emergence of multidrug-resistant strains. Highly lethal outbreaks of extensively drugresistant tuberculosis among HIVinfected persons in South Africa demonstrate the public health emergency that results when these two forces converge in the same setting. Fortunately, at this time of great need, tuberculosis drug development has been roused from its decades-long slumber. New ways of using existing drugs and the development of new drug classes hold great promise for the treatment of both drug-susceptible and drug-resistant tuberculosis. Children are a critical part of the global tuberculosis pandemic, with an estimated 900,000 cases and 100,000 deaths per year.en_ZA
dc.description.versionPublishers' Versionen_ZA
dc.format.extentp. 1168-1172 : ill.
dc.identifier.citationBurman, W. J. et al. 2008. Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens. PLoS Med, 5(8), e176:1168-1172 , doi:10.1371/journal.pmed.0050176.en_ZA
dc.identifier.issn1549-1676 (online)
dc.identifier.issn1549-1277 (print)
dc.identifier.otherdoi:10.1371/journal.pmed.0050176
dc.identifier.urihttp://hdl.handle.net/10019.1/21891
dc.language.isoen_ZAen_ZA
dc.publisherPublic Library of Science (PLOS)en_ZA
dc.rights.holderAuthor retains the copyrighten_ZA
dc.subjectChildren illnessesen_ZA
dc.subjectTuberculosisen_ZA
dc.subjectTuberculosis in children -- Treatmenten_ZA
dc.titleEnsuring the involvement of children in the evaluation of new tuberculosis treatment regimensen_ZA
dc.typeArticleen_ZA
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